Adam Hofri-Winogradow specializes in inter-generational wealth transfer and the bodies of law regulating it: trusts and estates, fiduciary law, "elder law", pensions, insurance, and relevant issues of tax and family law. He is the first Israeli academic to specialize in trusts law. Adam also specializes in corporate law. 
Adam makes intensive use of empirical research methods. He published research on the recent reform and transformation of trust law and trust practice in dozens of countries worldwide. Other work addressed the uses made of private trusts in Israel and, earlier, Palestine, Eighteenth Century English law, Adam Smith and the Scottish Enlightenment. Yet other works address the current rise, in Israel, of non-state halachic adjudication in private law matters.

Since 2008, Adam is a member of STEP - the Society of Trusts and Estates Practitioners. He received that organization's Diploma in International Trust Management in 2010. He is also a member of the American Law & Economics Association, the American Bar Association, Real Property, Trusts and Estates Section, and the Equity & Trusts Research Network at the University of Kent.
During Fall 2013, Adam was a Visiting Professor at Georgetown Law Center, as well as at the Centre for Transnational Legal Studies in London, UK.
In 2015, the University of Connecticut School of Law appointed Adam as its Martin Flynn Global Law Professor.
In 2017-2018 Adam was a Visiting Professor at Western Ontario University, Faculty of Law.
He won the Cegla prize in 2010 and the Zeltner Prize for Young Researchers in 2017.