@article {2984,
	title = {Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans.},
	journal = {Mol Biol Cell},
	volume = {13},
	number = {3},
	year = {2002},
	month = {2002 Mar},
	pages = {892-901},
	abstract = {Mutations in the Caenorhabditis elegans unc-84 gene cause defects in nuclear migration and anchoring. We show that endogenous UNC-84 protein colocalizes with Ce-lamin at the nuclear envelope and that the envelope localization of UNC-84 requires Ce-lamin. We also show that during mitosis, UNC-84 remains at the nuclear periphery until late anaphase, similar to known inner nuclear membrane proteins. UNC-84 protein is first detected at the 26-cell stage and thereafter is present in most cells during development and in adults. UNC-84 is properly expressed in unc-83 and anc-1 lines, which have phenotypes similar to unc-84, suggesting that neither the expression nor nuclear envelope localization of UNC-84 depends on UNC-83 or ANC-1 proteins. The envelope localization of Ce-lamin, Ce-emerin, Ce-MAN1, and nucleoporins are unaffected by the loss of UNC-84. UNC-84 is not required for centrosome attachment to the nucleus because centrosomes are localized normally in unc-84 hyp7 cells despite a nuclear migration defect. Models for UNC-84 localization are discussed.},
	keywords = {Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Centrosome, Gene Expression Regulation, Developmental, Helminth Proteins, Lamins, Membrane Glycoproteins, Membrane Proteins, Mitosis, Models, Biological, Nuclear Envelope, Nuclear Pore Complex Proteins, Nuclear Proteins, Recombinant Fusion Proteins, Thymopoietins},
	issn = {1059-1524},
	doi = {10.1091/mbc.01-06-0294},
	author = {Lee, Kenneth K and Starr, Daniel and Cohen, Merav and Liu, Jun and Han, Min and Wilson, Katherine L and Gruenbaum, Yosef}
}
