@article {1907,
	title = {Effect of cationic and anionic polyelectrolytes and antibodies on the lysis of micrococci and streptococci by leukocyte lysates and lysozyme},
	journal = {Israel Journal of Medical Sciences},
	volume = {9},
	number = {5},
	year = {1973},
	pages = {663-668},
	abstract = {In previous reports (1-3), it has been shown
that lysosomal enzymes derived from a variety
of mammalian leukocyte populations degrade
14C-Iabeled Micrococcus lysodeikticus and
Staphylococcus albus extensively. On the other
hand, group A streptococci are very resistant
to lysis by leukocyte lysates. It has also been
shown that, unlike S. albus and M. lysodeikticus,
streptococci which are resistant to lysis
in vitro persist for long periods in granulomatous
lesions in mouse and rabbit tissues
(1, 2). Other reports (4, 5) have shown that
bacteria coated with specific antibodies are
degraded at a slower rate following phagocytosis,
as compared with untreated bacteria.
Cationic polyelectrolytes, such as polylysine
and polyarginine, agglutinate a variety of
bacteria (6), and cationic proteins derived
from leukocytes as well as from calf thymus
histone are bactericidal for a variety of microorganisms
(7). The possibility was therefore
investigated that, by analogy to antibodies,
cationic proteins may coat bacterial cells and
thus interfere with their degradation by leukocyte
lysosomal enzymes.},
	author = {Isaac Ginsburg and N. Ne{\textquoteright}eman and Meir Lahav}
}
