Edible compositions capable of removing oral biofilm.

Abstract:

An edible and/or chewable article contg. at least one food grade substance having adsorption affinity towards at least one dental plaque (biofilm) constituent and capable of reducing and/or removing the oral biofilm while present in the mouth is described. Particular articles are chewing gums, sweets, candies, candy- and other nutritional bars, ice creams, chocolates, confectionery and bakery/pastry products, honey, dairy products and beverages, and oral hygiene products such as tooth pastes, oral gels and mouthwashes. A chewing gum comprises a conventional gum base and at least one food grade active substance having adsorption affinity towards at least one dental plaque (biofilm) constituent (bacteria and proteins and bacterial cell-free enzymes) and capable of reducing and/or removing the oral biofilm while present in the mouth. Typical active substances are polysaccharides and non-toxic salts thereof, such as alginates, chitosan, CM-cellulose, agar and carrageenan, inorg. substances such as silica, hydroxyapatite and calcium carbonate, and proteins, particularly gelatin and lectin. The chewing gum and other articles are particularly intended for removing and/or for preventing or reducing dental plaque (biofilm), and controlling oral, dental and periodontal diseases. For example, chewing gum base contg. sodium alginate exhibited high binding properties for Streptococcus mutans, av. of 2000% compared to the gum base without the alginate (control = 100% adhesion). Other polysaccharides, such as carrageenan, agar, sodium CM-cellulose and chitosan also exhibited higher adsorption than the control chewing gum base, but less than the alginate (500%, 510%, 600%, and 400%, resp.). [on SciFinder(R)]

Notes:

CAPLUS AN 2003:570777(Patent)