Formation and properties of surface-active antibodies


Magdassi S, Sheinberg O, Zakay-Rones Z. Formation and properties of surface-active antibodies. In: Proteins at Interfaces II- ACS Symposium Series. Vol. 602. American Chemical Society ; 1995. pp. 533 - 40.


Surface active antibodies were formed by covalent attachment of hydrophobic groups to the IgG mol. The modified antibodies reduced surface tension and adsorbed onto emulsion droplets at surface concns. higher than the native antibody. The chem. modification led to a decrease in the biol. activity; however, at specific conditions, surface-active antibodies, which retained their recognition ability, could be formed. By using these antibodies, a new emulsion, which has a specific recognition ability for HSV-1 infected cells, was formed. [on SciFinder(R)]


CAPLUS AN 1995:965797(Journal)

Last updated on 05/04/2016