Novaluron nanoparticles: Formation and potential use in controlling agricultural insect pests

Citation:

Elek N, Hoffman R, Raviv U, Resh R, Ishaaya I, Magdassi S. Novaluron nanoparticles: Formation and potential use in controlling agricultural insect pests. Colloids and Surfaces A: Physicochemical and Engineering Aspects [Internet]. 2010;372 :66 - 72.

Date Published:

2010/1/1/2010///

Abstract:

Nanoparticles of novaluron, a water-insoluble insecticide, were prepared by a novel method, based on a direct conversion of O/W microemulsions containing pesticide and volatile solvents, into powders. The conversion of nanoparticles into powder was achieved by rapid evaporation of all the liquids in the microemulsion by spray drying. The microemulsions were evaluated by SAXS, self diffusion NMR, conductivity, and viscosity. The droplet size was approximately 6nm, and the novaluron particle size, after redispersion and evaluation by DLS, was 200±50nm. These particles consisted of aggregates of nanoparticles (30–100nm), as viewed by Cryo-TEM. Electron diffraction and XRD showed that the nanoparticles were amorphous indicating a possible improved bioactivity. The stability of the dispersed nanoparticles was evaluated by following particle size by DLS for a period of time, revealing a slight increase in particle size despite the high value of zeta potential. In vivo experiments carried out with Egyptian cotton leafworm Spodoptera littoralis larvae indicated that the toxicity of nanoparticles of novaluron resembled that of the commercial formulation.

Notes:

Accession Number: S0927775710005509; Author: Elek, Naomi (a); Author: Hoffman, Roy (b); Author: Raviv, Uri (b); Author: Resh, Roy (b); Author: Ishaaya, Isaac (c); Author: Magdassi, Shlomo (a, ⁎); Affiliation: Casali Institute of Applied Chemistry, Institute of Chemistry, Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel; Affiliation: Institute of Chemistry, Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel; Affiliation: Department of Entomology, Agricultural Research Organization, The Volcani Center, Bet Dagan 50250, Israel; Number of Pages: 7; Language: English;

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