Mattan Hurevich

Dr. Mattan Hurevich

Senior lecturer at The Hebrew University of Jerusalem, Faculty of Science, The Institute of Chemistry
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Academic career:

B.Sc., 2001, The Hebrew University of Jerusalem; M.Sc., 2004, The Hebrew University of Jerusalem Ph.D., 2010, The Hebrew University of (advisor: Chaim Gilon); Postdoctoral Training, 2010-2014, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany (advisor: Peter H. Seeberger); 2015-2017, Senior scientists, The Hebrew University of Jerusalem; Assistant Professor, 2017-present, The Hebrew University of Jerusalem 

Research interests:

  • Automated and photochemical synthesis of oligosaccharides, N- / O- glycopeptides
  • Syntheses of multi phosphorylated peptides
  • Development of biosensors based on oligosaccharide, peptides and glycopeptides
  • Enzymatic glycosylation and hydrolysis of oligosaccharides

Personal details: Mattan was born and lives in Jerusalem, Israel. He is married and a proud father of two lovely daughters. His non-scientific time is devoted to Manchester United, Tom Waits, hiking, camping and reading books.

Selected publications:

A zinc selective oxytocin based biosensor. Mervinejsky, E., et al. J Mat Chem B., 8, 155-160 (2020).

The Breaking Beads Approach for Photocleavage from Solid Support.  Bakhatan et al. Org Biomol Chem, in press

Diffusion enhanced amide bond formation on solid support. Naoum, J., et al. ACS Org Proc Res Dev., 23, 2733-2739 (2019).

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation. Mayer, D., et al. Nat Comm., 10, 1261 (2019).

A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins. Samarasimhareddy, M., et al. Org Biomol Chem., 14, 1860-1865 (2019).

Sulfation Patterns of Saccharides and Heavy Metal Ion Binding. Alshanski, I., et al. Chem Eur J., 25, 12083-12090 (2019).

Direct Assembly and Metal-Ion Binding Properties of Oxytocin Monolayer on Gold Surfaces. Mervinejsky, E., et al. Langmuir., 35, 11114-11122 (2019).

Electron Transport through Self-Assembled Monolayers of Tripeptides.. Mervinetsky, E., et al. JPCC., 123, 9600-9608 (2019).

Enhancing the Efficiency of the Solid Phase Peptide Synthesis (SPPS) Process by High Shear Mixing. Alshanski, I., et al. ACS Org Proc Res Dev., 22, 1318-1322 (2018).

Automated glycan assembly using the Glyconeer 2.1 synthesizer. Hahm, H.S., et al. PNAS., 114, 3385-3389 (2017).

Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages. Hahm, H.S., et al. Nat Comm., 7, 12482 (2016).

Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis. Hurevich, M., et al. Chem Comm., 50, 1851-1853 (2014).

 

Contact Information

Los Angeles Building; Room 312
Givat Ram Campus
Jerusalem ,91904, Israel
p: 972-26586201