%0 Journal Article %D 2023 %T Effect of ionic strength on the assembly of simian vacuolating virus capsid protein around poly(styrene sulfonate) %A Asor, Roi %A Singaram, Surendra W. %A Levi-Kalisman, Yael %A Hagan, Michael F. %A Raviv, Uri %X

Virus-like particles (VLPs) are noninfectious nanocapsules that can be used for drug delivery or vaccine applications. VLPs can be assembled from virus capsid proteins around a condensing agent, such as RNA, DNA, or a charged polymer. Electrostatic interactions play an important role in the assembly reaction. VLPs assemble from many copies of capsid protein, with a combinatorial number of intermediates. Hence, the mechanism of the reaction is poorly understood. In this paper, we combined solution small-angle X-ray scattering (SAXS), cryo-transmission electron microscopy (TEM), and computational modeling to determine the effect of ionic strength on the assembly of Simian Vacuolating Virus 40 (SV40)-like particles. We mixed poly(styrene sulfonate) with SV40 capsid protein pentamers at different ionic strengths. We then characterized the assembly product by SAXS and cryo-TEM. To analyze the data, we performed Langevin dynamics simulations using a coarse-grained model that revealed incomplete, asymmetric VLP structures consistent with the experimental data. We found that close to physiological ionic strength, $$T=1$$VLPs coexisted with VP1 pentamers. At lower or higher ionic strengths, incomplete particles coexisted with pentamers and $$T=1$$particles. Including the simulated structures was essential to explain the SAXS data in a manner that is consistent with the cryo-TEM images.

%V 46 %P 107 %8 2023 %@ 1292-895X %G eng %U https://doi.org/10.1140/epje/s10189-023-00363-x %N 11 %! The European Physical Journal E %0 Journal Article %J Journal of Structural Biology %D 2023 %T Insight into structural biophysics from solution X-ray scattering %A Raviv, Uri %A Asor, Roi %A Shemesh, Asaf %A Ginsburg, Avi %A Ben-Nun, Tal %A Schilt, Yaelle %A Levartovsky, Yehonatan %A Israel Ringel %K SAXS %K Self-assembly %K Time-resolved SAXS %K WAXS %X

The current challenges of structural biophysics include determining the structure of large self-assembled complexes, resolving the structure of ensembles of complex structures and their mass fraction, and unraveling the dynamic pathways and mechanisms leading to the formation of complex structures from their subunits. Modern synchrotron solution X-ray scattering data enable simultaneous high-spatial and high-temporal structural data required to address the current challenges of structural biophysics. These data are complementary to crystallography, NMR, and cryo-TEM data. However, the analysis of solution scattering data is challenging; hence many different analysis tools, listed in the SAS Portal (http://smallangle.org/), were developed. In this review, we start by briefly summarizing classical X-ray scattering analyses providing insight into fundamental structural and interaction parameters. We then describe recent developments, integrating simulations, theory, and advanced X-ray scattering modeling, providing unique insights into the structure, energetics, and dynamics of self-assembled complexes. The structural information is essential for understanding the underlying physical chemistry principles leading to self-assembled supramolecular architectures and computational structural refinement.

%B Journal of Structural Biology %V 215 %P 108029 %G eng %U https://www.sciencedirect.com/science/article/pii/S1047847723000928 %N 4 %R https://doi.org/10.1016/j.jsb.2023.108029 %0 Journal Article %J Journal of Applied Crystallography %D 2023 %T Upgrade of ıt D+ software for hierarchical modeling of X-ray scattering data from complex structures in solution, fibers and single orientations} %A Balken, Eytan %A Ben-Nun, Itai %A Amos Fellig %A Khaykelson, Daniel %A Raviv, Uri %K D+ software %K fiber diffraction %K hierarchical modeling %K orientations %K polydispersity %K structure factors %K X-ray scattering %X

This article presents an upgrade of the ıt D}+ software [Ginsburg ıt et al.} (2019). ıt J. Appl. Cryst.} \bf 52, 219–242], expanding its hierarchical solution X-ray scattering modeling capabilities for fiber diffraction and single crystallographic orientations. This upgrade was carried out using the reciprocal grid algorithm [Ginsburg ıt et al.} (2016). ıt J. Chem. Inf. Model.} \bf 56, 1518–1527], providing ıt D}+ its computational strength. Furthermore, the extensive modifications made to the Python API of ıt D}+ are described, broadening the X-ray analysis performed with ıt D}+ to account for the effects of the instrument-resolution function and polydispersity. In addition, structure-factor and radial-distribution-function modules were added, taking into account the effects of thermal fluctuations and intermolecular interactions. Finally, numerical examples demonstrate the usage and potential of the added features.

%B Journal of Applied Crystallography %V 56 %P 1295–1303 %8 Aug %G eng %U https://doi.org/10.1107/S1600576723005319 %N 4 %R 10.1107/S1600576723005319 %0 Journal Article %J Proceedings of the National Academy of Sciences %D 2023 %T Modulating amyloids’ formation path with sound energy %A Kozell, Anna %A Eliaz, Dror %A Solomonov, Aleksei %A Benyamin, Doron %A Shmul, Guy %A Brookstein, Ori %A Rosenhek-Goldian, Irit %A Raviv, Uri %A Shimanovich, Ulyana %B Proceedings of the National Academy of Sciences %I National Acad Sciences %V 120 %P e2212849120 %@ 0027-8424 %G eng %U https://www.pnas.org/doi/abs/10.1073/pnas.2212849120 %N 3 %0 Journal Article %J Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics %D 2023 %T Effect of tubulin self-association on GTP hydrolysis and nucleotide exchange reactions %A Shemesh, Asaf %A Ghareeb, Hiba %A Dharan, Raviv %A Levi-Kalisman, Yael %A Norman Metanis %A Israel Ringel %A Raviv, Uri %K GDP %K GMP %K GTP %K GTP hydrolysis %K Nucleotide exchange %K Tubuin %X

We investigated how the self-association of isolated tubulin dimers affects the rate of GTP hydrolysis and the equilibrium of nucleotide exchange. Both reactions are relevant for microtubule (MT) dynamics. We used HPLC to determine the concentrations of GDP and GTP and thereby the GTPase activity of SEC-eluted tubulin dimers in assembly buffer solution, free of glycerol and tubulin aggregates. When GTP hydrolysis was negligible, the nucleotide exchange mechanism was studied by determining the concentrations of tubulin-free and tubulin-bound GTP and GDP. We observed no GTP hydrolysis below the critical conditions for MT assembly (either below the critical tubulin concentration and/or at low temperature), despite the assembly of tubulin 1D curved oligomers and single-rings, showing that their assembly did not involve GTP hydrolysis. Under conditions enabling spontaneous slow MT assembly, a slow pseudo-first-order GTP hydrolysis kinetics was detected, limited by the rate of MT assembly. Cryo-TEM images showed that GTP-tubulin 1D oligomers were curved also at 36 °C. Nucleotide exchange depended on the total tubulin concentration and the molar ratio between tubulin-free GDP and GTP. We used a thermodynamic model of isodesmic tubulin self-association, terminated by the formation of tubulin single-rings to determine the molar fractions of dimers with exposed and buried nucleotide exchangeable sites (E-sites). Our analysis shows that the GDP to GTP exchange reaction equilibrium constant was an order-of-magnitude larger for tubulin dimers with exposed E-sites than for assembled dimers with buried E-sites. This conclusion may have implications on the dynamics at the tip of the MT plus end.

%B Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics %V 1871 %P 140869 %G eng %U https://www.sciencedirect.com/science/article/pii/S1570963922001169 %N 2 %R https://doi.org/10.1016/j.bbapap.2022.140869 %0 Journal Article %J Nature Communications %D 2022 %T Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers %A Eliaz, D. %A Paul, S. %A Benyamin, D. %A Cernescu, A. %A Cohen, S. R. %A Rosenhek-Goldian, I. %A Brookstein, O. %A Miali, M. E. %A Solomonov, A. %A Greenblatt, M. %A Levy, Y. %A Raviv, U. %A Barth, A. %A Shimanovich, U. %X

Silk is a unique, remarkably strong biomaterial made of simple protein building blocks. To date, no synthetic method has come close to reproducing the properties of natural silk, due to the complexity and insufficient understanding of the mechanism of the silk fiber formation. Here, we use a combination of bulk analytical techniques and nanoscale analytical methods, including nano-infrared spectroscopy coupled with atomic force microscopy, to probe the structural characteristics directly, transitions, and evolution of the associated mechanical properties of silk protein species corresponding to the supramolecular phase states inside the silkworm’s silk gland. We found that the key step in silk-fiber production is the formation of nanoscale compartments that guide the structural transition of proteins from their native fold into crystalline β-sheets. Remarkably, this process is reversible. Such reversibility enables the remodeling of the final mechanical characteristics of silk materials. These results open a new route for tailoring silk processing for a wide range of new material formats by controlling the structural transitions and self-assembly of the silk protein’s supramolecular phases.

%B Nature Communications %V 13 %P 7856 %8 2022 %@ 2041-1723 %G eng %U https://doi.org/10.1038/s41467-022-35505-w %N 1 %! Nature Communications %0 Journal Article %J Nanoscale %D 2022 %T Dehydration does not affect lipid-based hydration lubrication %A Dong, Yihui %A Kampf, Nir %A Schilt, Yaelle %A Cao, Wei %A Raviv, Uri %A Jacob Klein %B Nanoscale %I Royal Society of Chemistry %G eng %0 Journal Article %J The Journal of Physical Chemistry Letters %D 2022 %T Mechanism of the Initial Tubulin Nucleation Phase %A Shemesh, Asaf %A Dharan, Nadiv %A Ginsburg, Avi %A Dharan, Raviv %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %B The Journal of Physical Chemistry Letters %V 13 %P 9725-9735 %G eng %U https://doi.org/10.1021/acs.jpclett.2c02619 %N 41 %R 10.1021/acs.jpclett.2c02619 %0 Journal Article %J The Journal of Physical Chemistry Letters %D 2022 %T Mechanism of Tubulin Oligomers and Single-Ring Disassembly Catastrophe %A Shemesh, Asaf %A Ginsburg, Avi %A Dharan, Raviv %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %B The Journal of Physical Chemistry Letters %V 13 %P 5246-5252 %G eng %U https://doi.org/10.1021/acs.jpclett.2c00947 %N 23 %R 10.1021/acs.jpclett.2c00947 %0 Journal Article %J ChemRxiv %D 2022 %T Mechanism of Tubulin Oligomers and Single-Rings Disassembly Catastrophe %A Shemesh, Asaf %A Ginsburg, Avi %A Dharan, Raviv %A Kalisman-Levi, Yael %A Israel Ringel %A Raviv, Uri %B ChemRxiv %G eng %U https://chemrxiv.org/engage/chemrxiv/article-details/610952b3d03b3d5d6404d4ae %0 Journal Article %J bioRxiv %D 2022 %T Effect of Ionic Strength on the Assembly of Simian Vacuolating Virus Capsid Protein Around Poly(Styrene Sulfonate) %A Asor, Roi %A Singaram, Surendra Walter %A Levi-Kalisman, Yael %A Hagan, Michael Francis %A Raviv, Uri %X

{Virus-like particles (VLPs) are noninfectious nanocapsules that can be used for drug delivery or vaccine applications. VLPs can be assembled from virus capsid proteins around a condensing agent like RNA, DNA, or a charged polymer. Electrostatic interactions play an important role in the assembly reaction. VLPs assemble from many copies of capsid protein, with combinatorial intermediates, and therefore the mechanism of the reaction is poorly understood. In this paper, we determined the effect of ionic strength on the assembly of Simian Vacuolating Virus 40 (SV40)-like particles. We mixed poly(styrene sulfonate) with SV40 capsid protein pentamers at different ionic strengths. We then characterized the assembly product by solution small-angle X-ray scattering (SAXS) and cryo-TEM. To analyze the data, we performed Brownian dynamics simulations using a coarse-grained model that revealed incomplete, asymmetric VLP structures that were consistent with the experimental data. We found that close to physiological ionic strength

%B bioRxiv %I Cold Spring Harbor Laboratory %G eng %U https://www.biorxiv.org/content/early/2022/02/25/2022.02.25.481942 %R 10.1101/2022.02.25.481942 %0 Journal Article %J ChemRxiv %D 2021 %T Effect of Tubulin Self-Association on GTP Hydrolysis and Nucleotide Exchange Reactions %A Sadeh, Asaf Shemesh %A Dharan, Raviv %A Ghareeb, Hiba %A Norman Metanis %A Israel Ringel %A Raviv, Uri %B ChemRxiv %G eng %U https://chemrxiv.org/engage/chemrxiv/article-details/610b931c03182fce3f19cf40 %0 Journal Article %J ACS Chemical Biology %D 2021 %T Structure and Energetics of GTP- and GDP-Tubulin Isodesmic Self-Association %A Shemesh, Asaf %A Ginsburg, Avi %A Dharan, Raviv %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %B ACS Chemical Biology %V 16 %P 2212–2227 %G eng %U https://doi.org/10.1021/acschembio.1c00369 %N 11 %R 10.1021/acschembio.1c00369 %0 Journal Article %J ACS Nano %D 2021 %T Hierarchical Assembly Pathways of Spermine-Induced Tubulin Conical-Spiral Architectures %A Dharan, Raviv %A Shemesh, Asaf %A Millgram, Abigail %A Zalk, Ran %A Frank, Gabriel A. %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %B ACS Nano %V 15 %P 8836–8847 %G eng %U https://doi.org/10.1021/acsnano.1c01374 %N 5 %R 10.1021/acsnano.1c01374 %0 Journal Article %J Biochimica et Biophysica Acta (BBA) - General Subjects %D 2021 %T Effect of the ammonium salt anion on the structure of doxorubicin complex and PEGylated liposomal doxorubicin nanodrugs %A Schilt, Yaelle %A Tal Berman %A Xiaohui Wei %A Einat Nativ-Roth %A Barenholz, Yechezkel %A Raviv, Uri %K Confinement %K Palmar-plantar Erythrodysesthesia %K PEGylated liposomal doxorubicin %K SAXS %K WAXS %X

Background In Doxil®, PEGylated nanoliposomes are created by hydration of the lipids in ammonium sulfate, and are remotely loaded with doxorubicin by a transmembrane ammonium gradient. The ammonium sulfate is then removed from the external aqueous phase, surrounding the liposomes, and replaced by an isoosmotic sucrose solution in 10 mM histidine buffer at pH 6.5. Methods We prepared PEGylated liposomal doxorubicin (PLD) with a series of ammonium monovalent salts that after remote loading became the intraliposome doxorubicin counteranions. We analyzed the liposomes by solution X-ray scattering, differential scanning calorimetry, and electron micropscopy. Results PLDs prepared with sulfonic acid derivatives as counteranion exhibited chemical and physical stabilities. We determined the effect of these ammonium salt counteranions on the structure, morphology, and thermotropic behavior of the PEGylated nanoliposomes, formed before and after doxorubicin loading, and the bulk properties of the doxorubicin-counteranion complexes. By comparing the structure of the doxorubicin complexes in the bulk and inside the nanoliposomes, we revealed the effect of confinement on the structure and doxorubicin release rate for each of the derivatives of the ammonium sulfonic acid counteranions. Conclusions We found that the extent and direction of the doxorubicin confinement effect and its release rate were strongly dependent on the type of counteranion. The counteranions, however, neither affected the structure and thermotropic behavior of the liposome membrane, nor the thickness and density of the liposome PEG layers. In an additional study, it was demonstrated that PLD made with ammonium-methane sulfonate exhibit a much lower Hand and Foot syndrome. General significance The structure, physical state, and pharmacokinetics of doxorubicin in PEGylated nanoliposomes, prepared by transmembrane remote loading using gradients of ammonium salts, strongly depend on the counteranions.

%B Biochimica et Biophysica Acta (BBA) - General Subjects %V 1865 %P 129849 %G eng %U http://www.sciencedirect.com/science/article/pii/S0304416521000088 %N 5 %R https://doi.org/10.1016/j.bbagen.2021.129849 %0 Journal Article %J Langmuir %D 2020 %T Bridges of Calcium Bicarbonate Tightly Couple Dipolar Lipid Membranes %A Fink, Lea %A Allolio, Christoph %A Feitelson, Jehuda %A Tamburu, Carmen %A Harries, Daniel %A Raviv, Uri %B Langmuir %V 36 %P 10715–10724 %G eng %U https://doi.org/10.1021/acs.langmuir.0c01511 %N 36 %R 10.1021/acs.langmuir.0c01511 %0 Journal Article %J Nano Letters %D 2020 %T 3D Printing of ordered mesoporous silica complex structures %A Shukrun Farrell, Efrat %A Schilt, Yaelle %A Moshkovitz, May Yam %A Levi-Kalisman, Yael %A Raviv, Uri %A Magdassi, Shlomo %B Nano Letters %V 20 %P 6598–6605 %G eng %U https://doi.org/10.1021/acs.nanolett.0c02364 %N 9 %R 10.1021/acs.nanolett.0c02364 %0 Journal Article %J ACS Nano %D 2020 %T Assembly and Stability of Simian Virus 40 Polymorphs %A Waltmann, Curt %A Asor, Roi %A Raviv, Uri %A Olvera de la Cruz, Monica %B ACS Nano %V 14 %P 4430-4443 %G eng %U https://doi.org/10.1021/acsnano.9b10004 %N 4 %R 10.1021/acsnano.9b10004 %0 Journal Article %J Journal of the American Chemical Society %D 2020 %T Rapidly Forming Early Intermediate Structures Dictate the Pathway of Capsid Assembly %A Asor, Roi %A Schlicksup, Christopher John %A Zhao, Zhongchao %A Zlotnick, Adam %A Raviv, Uri %B Journal of the American Chemical Society %V 142 %P 7868–7882 %G eng %U https://doi.org/10.1021/jacs.0c01092 %N 17 %R 10.1021/jacs.0c01092 %0 Journal Article %J Soft Matter %D 2020 %T pH Stability and Disassembly Mechanism of Wild-Type Simian Virus 40 %A Asor, Roi %A Khaykelson, Daniel %A Ben-nun-Shaul, Orly %A Levi-Kalisman, Yael %A Oppenheim, Ariella %A Raviv, Uri %X

Virus are remarkable self-assembled nanobiomaterial-based machines, exposed to a wide range of pH values. Extreme pH values can induce dramatic structural changes, critical for the function of the virus nanoparticles including assembly and genome uncoating. Tuning cargo - capsid interactions is essential for designing viral-based delivery systems. Here we show how pH controls the structure and activity of wild-type simian virus 40 (wtSV40) and the interplay between its cargo and capsid. Using cryo-TEM and solution X-ray scattering, we found that wtSV40 was stable between pH 5.5 and 9, and only slightly swelled with increasing pH. At pH 3, the particles aggregated, while capsid protein pentamers continued to coat the virus cargo but lost their positional correlations. Infectivity was only partly lost after the particles had been returned to pH 7. At pH 10 or higher, the particles were unstable, lost their infectivity, and disassembled. Using time-resolved experiments we discovered that disassembly began by swelling of the particles, poking a hole in the capsid through which the genetic cargo escaped, and followed by a slight shrinking of the capsids and complete disassembly. These findings provide insight into the fundamental intermolecular forces, essential for SV40 function, and for designing virus-based nanobiomaterials, including delivery systems and antiviral drugs.

%B Soft Matter %I The Royal Society of Chemistry %V 16 %P 2803-2814 %G eng %U http://dx.doi.org/10.1039/C9SM02436K %N 11 %R 10.1039/C9SM02436K %0 Journal Article %J Biophysical Reviews %D 2020 %T Studying viruses using solution X-ray scattering %A Khaykelson, Daniel %A Raviv, Uri %X

Viruses have been of interest to mankind since their discovery as small infectious agents in the nineteenth century. Because many viruses cause diseases to humans and agriculture, they were rigorously studied for biological and medical purposes. Viruses have remarkable properties such as the symmetry and self-assembly of their protein envelope, maturation into infectious virions, structural stability, and disassembly. Solution X-ray scattering can probe structures and reactions in solutions, down to subnanometer spatial resolution and millisecond temporal resolution. It probes the bulk solution and reveals the average shape and average mass of particles in solution and can be used to study kinetics and thermodynamics of viruses at different stages of their life cycle. Here we review recent work that demonstrates the capabilities of solution X-ray scattering to study in vitro the viral life cycle.

%B Biophysical Reviews %V 12 %P 41–48 %8 Feb %G eng %U https://doi.org/10.1007/s12551-020-00617-4 %R 10.1007/s12551-020-00617-4 %0 Journal Article %D 2019 %T Hierarchical Assembly Pathways of Spermine Induced Tubulin Conical-Spiral Architectures %A Dharan, Raviv %A Shemesh, Asaf %A Millgram, Abigail %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %8 12 %G eng %U https://chemrxiv.org/articles/Hierarchical_Assembly_Pathways_of_Spermine_Induced_Tubulin_Conical-Spiral_Architectures/11353166 %R 10.26434/chemrxiv.11353166.v1 %0 Journal Article %J J. Phys. Chem. C %D 2019 %T Synthesis and Characterization of Thiolate-Protected Gold Nanoparticles of Controlled Diameter %A Lior Shaltiel %A Shemesh, Asaf %A Raviv, Uri %A Barenholz, Yechezkel %A Levi-Kalisman, Yael %B J. Phys. Chem. C %V 123 %P 28486-28493 %G eng %U https://pubs.acs.org/doi/full/10.1021/acs.jpcc.9b08817 %N 46 %0 Journal Article %J Langmuir %D 2019 %T Minireview-Microtubule and Tubulin Oligomers: Shape Transitions and Assembly by Intrinsically Disordered Protein Tau and Cationic Biomolecules %A Cyrus R. Safinya %A Peter J. Chung %A Song, Chaeyeon %A Li, Youli %A Herbert P. Miller %A Choi, Myung Chul %A Raviv, Uri %A Ewert, Kai K %A Wilson, Leslie %A Feinstein, Stuart C %B Langmuir %V 35 %P 15970–15978 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.9b02208 %N 48 %0 Journal Article %J Langmuir %D 2019 %T Structure and Interactions between Charged Lipid Membranes in the Presence of Multivalent Ions %A Fink, Lea %A Steiner, Ariel %A Szekely, Or %A Szekely, Pablo %A Raviv, Uri %B Langmuir %V 35 %P 9694-9703 %G eng %U https://pubs.acs.org/doi/10.1021/acs.langmuir.9b00778 %N 30 %0 Journal Article %J ACS Nano %D 2019 %T Assembly Reactions of Hepatitis B Capsid Protein into Capsid Nanoparticles Follow a Narrow Path Through a Complex Reaction Landscape %A Asor, Roi %A Selzer, Lisa %A Schlicksup, Christopher John %A Zhao, Zhongchao %A Zlotnick, Adam %A Raviv, Uri %B ACS Nano %V 13 %P 7610-7626 %G eng %U https://pubs.acs.org/doi/10.1021/acsnano.9b00648 %N 7 %0 Journal Article %J Journal of Virology %D 2019 %T Structural differences between the Woodchuck hepatitis virus core protein in dimer and capsid states are consistent with entropic and conformational regulation of assembly %A Zhao, Z %A Che-Yen Wang, J %A Gonzalez-Gutierrez, G %A Venkatakrishnan, B %A Asor, R %A Khaykelson, D %A Raviv, U %A Zlotnick, A %B Journal of Virology %P JVI.00141-19 %G eng %U https://jvi.asm.org/content/early/2019/04/25/JVI.00141-19.abstract %0 Journal Article %J Journal of Applied Crystallography %D 2019 %T D+: software for high-resolution hierarchical modeling of solution X-ray scattering from complex structures %A Ginsburg, Avi %A Ben-Nun, Tal %A Asor, Roi %A Shemesh, Asaf %A Fink, Lea %A Tekoah, Roee %A Levartovsky, Yehonatan %A Khaykelson, Daniel %A Dharan, Raviv %A Amos Fellig %A Raviv, Uri %B Journal of Applied Crystallography %V 52 %P 219-242 %G eng %U https://scripts.iucr.org/cgi-bin/paper?vg5099 %N 1 %0 Journal Article %J ACS Omega %D 2019 %T Effect of Calcium Ions and Disulfide Bonds on Swelling of Virus Particles %A Asor, Roi %A Khaykelson, Daniel %A Ben-nun-Shaul, Orly %A Oppenheim, Ariella %A Raviv, Uri %B ACS Omega %V 4 %P 58–64 %G eng %U https://pubs.acs.org/doi/10.1021/acsomega.8b02753 %N 1 %0 Journal Article %J Macromolecules %D 2019 %T Quasi-Two-Dimensional Assembly of Bottlebrush Block Copolymers with Nanoparticles in Ultrathin Films: Combined Effect of Graft Asymmetry and Nanoparticle Size %A Yaron Aviv %A Esra Altay %A Fink, Lea %A Raviv, Uri %A Javid Rzayev %A Shenhar, Roy %B Macromolecules %V 52 %P 196-207 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.macromol.8b01988 %N 1 %0 Journal Article %J ACS Omega %D 2018 %T Effect of Weakly Interacting Cosolutes on Lysozyme Conformations %A Levartovsky, Yehonatan %A Shemesh, Asaf %A Asor, Roi %A Raviv, Uri %B ACS Omega %V 3 %P 16246–16252 %G eng %U https://pubs.acs.org/doi/10.1021/acsomega.8b01289 %N 11 %0 Journal Article %J Biochemistry %D 2018 %T Structure, Assembly, and Disassembly of Tubulin Single Rings %A Shemesh, Asaf %A Ginsburg, Avi %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %B Biochemistry %V 57 %P 6153-6165 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.biochem.8b00560 %N 43 %0 Journal Article %J Angewandte Chemie %D 2018 %T Hydrophobicity Control in Adaptive Crystalline Assemblies %A Erez Cohen %A Yahel Soffer %A Haim Weissman %A Tatyana Bendikov %A Schilt, Yaelle %A Raviv, Uri %A Boris Rybtchinski %B Angewandte Chemie %V 130 %P 9009-9012 %G eng %U https://doi.org/10.1002/ange.201801912 %N 29 %0 Journal Article %J Biophysical journal %D 2018 %T Interacting Bacteria Surfaces %A Raviv, U %B Biophysical journal %V 114 %P 1515-1517 %G eng %U https://doi.org/10.1016/j.bpj.2018.03.010 %N 7 %0 Journal Article %J Biophysical journal %D 2017 %T Structure and Intermolecular Interactions between L-Type Straight Flagellar Filaments %A Louzon, Daniel %A Ginsburg, Avi %A Schwenger, Walter %A Dvir, Tom %A Dogic, Zvonimir %A Raviv, Uri %B Biophysical journal %I Elsevier %V 112 %P 2184-2195 %@ 0006-3495 %G eng %U https://doi.org/10.1016/j.bpj.2017.02.038 %N 10 %0 Book Section %B Methods in cell biology %D 2017 %T Synchrotron small-angle X-ray scattering and electron microscopy characterization of structures and forces in microtubule/Tau mixtures %A Chung, Peter J %A Song, Chaeyeon %A Miller, Herbert P %A Li, Youli %A Raviv, Uri %A Choi, Myung Chul %A Wilson, Leslie %A Feinstein, Stuart C %A Safinya, Cyrus R %B Methods in cell biology %I Academic Press %V 141 %P 155-178 %@ 0091-679X %G eng %U https://doi.org/10.1016/bs.mcb.2017.06.002 %0 Journal Article %J Proceedings of the National Academy of Sciences %D 2017 %T Changes in aggregation states of light-harvesting complexes as a mechanism for modulating energy transfer in desert crust cyanobacteria %A Eyal, Leeat Bar %A Choubeh, Reza Ranjbar %A Cohen, Eyal %A Eisenberg, Ido %A Tamburu, Carmen %A Dorogi, Márta %A Ünnep, Renata %A Appavou, Marie-Sousai %A Nevo, Reinat %A Raviv, Uri %A Reich, Ziv %A Garab, Győző %A Herbert van Amerongen %A Paltiel, Yossi %A Keren, Nir %B Proceedings of the National Academy of Sciences %I National Acad Sciences %V 114 %P 9481-9486 %@ 0027-8424 %G eng %U https://doi.org/10.1073/pnas.1708206114 %N 35 %0 Journal Article %J Langmuir %D 2017 %T Osmotic stress induced desorption of calcium ions from dipolar lipid membranes %A Fink, Lea %A Feitelson, Jehuda %A Noff, Roy %A Dvir, Tom %A Tamburu, Carmen %A Raviv, Uri %B Langmuir %I ACS Publications %V 33 %P 5636-5641 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.7b00596 %N 23 %0 Journal Article %J The Journal of Physical Chemistry B %D 2017 %T Structure of Dynamic, Taxol-Stabilized, and GMPPCP-Stabilized Microtubule %A Ginsburg, Avi %A Shemesh, Asaf %A Millgram, Abigail %A Dharan, Raviv %A Levi-Kalisman, Yael %A Israel Ringel %A Raviv, Uri %B The Journal of Physical Chemistry B %I ACS Publications %V 121 %P 8427-8436 %@ 1520-6106 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.jpcb.7b01057 %N 36 %0 Journal Article %J Photosynthesis research %D 2017 %T Concentration-based self-assembly of phycocyanin %A Eisenberg, Ido %A Harris, Dvir %A Levi-Kalisman, Yael %A Yochelis, Shira %A Shemesh, Asaf %A Ben-Nissan, Gili %A Sharon, Michal %A Raviv, Uri %A Adir, Noam %A Keren, Nir %B Photosynthesis research %I Springer %V 134 %P 39-49 %@ 0166-8595 %G eng %U https://link.springer.com/article/10.1007/s11120-017-0406-7 %N 1 %0 Journal Article %J ACS Nano %D 2017 %T Crystallization, Reentrant Melting, and Resolubilization of Virus Nanoparticles %A Asor, Roi %A Ben-nun-Shaul, Orly %A Oppenheim, Ariella %A Raviv, Uri %B ACS Nano %I ACS Publications %V 11 %P 9814-9824 %@ 1936-0851 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acsnano.7b03131 %N 10 %0 Journal Article %J Biochimica et Biophysica Acta (BBA)-General Subjects %D 2016 %T Using solution X-ray scattering to determine the high-resolution structure and morphology of PEGylated liposomal doxorubicin nanodrugs %A Schilt, Y %A Berman, T %A Wei, X %A Barenholz, Y. %A Raviv, U %B Biochimica et Biophysica Acta (BBA)-General Subjects %I Elsevier %V 1860 %P 108-119 %@ 0304-4165 %G eng %U https://doi.org/10.1016/j.bbagen.2015.09.012 %N 1 %0 Journal Article %J ACS Biomaterials Science & Engineering %D 2016 %T Wet Spinning and Drawing of Human Recombinant Collagen %A Yaari, Amit %A Schilt, Yaelle %A Tamburu, Carmen %A Raviv, Uri %A Shoseyov, Oded %B ACS Biomaterials Science & Engineering %I ACS Publications %V 2 %P 349-360 %@ 2373-9878 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.5b00461 %N 3 %0 Journal Article %J The Journal of Physical Chemistry A %D 2016 %T Critical Conditions for Adsorption of Calcium Ions onto Dipolar Lipid Membranes %A Lotan, Oren %A Fink, Lea %A Shemesh, Asaf %A Tamburu, Carmen %A Raviv, Uri %B The Journal of Physical Chemistry A %I ACS Publications %V 120 %P 3390-3396 %@ 1089-5639 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.jpca.6b02708 %N 19 %0 Journal Article %J Journal of chemical information and modeling %D 2016 %T Reciprocal grids: a hierarchical algorithm for computing solution x-ray scattering curves from supramolecular complexes at high resolution %A Ginsburg, Avi %A Ben-Nun, Tal %A Asor, Roi %A Shemesh, Asaf %A Israel Ringel %A Raviv, Uri %B Journal of chemical information and modeling %I ACS Publications %V 56 %P 1518-1527 %@ 1549-9596 %G eng %U https://pubs.acs.org/doi/abs/10.1021/acs.jcim.6b00159 %N 8 %0 Journal Article %J Journal of Parallel and Distributed Computing %D 2016 %T Spline-based parallel nonlinear optimization of function sequences %A Ben-Nun, Tal %A Barak, Amnon %A Raviv, Uri %B Journal of Parallel and Distributed Computing %I Elsevier %V 93 %P 132-145 %@ 0743-7315 %G eng %U https://doi.org/10.1016/j.jpdc.2016.04.011 %0 Journal Article %J Israel Journal of Chemistry %D 2016 %T Special Issue: Self‐Assembly of Biomolecules %A Raviv, Uri %B Israel Journal of Chemistry %I Wiley Online Library %V 56 %P 580-580 %@ 1869-5868 %G eng %U https://onlinelibrary.wiley.com/doi/full/10.1002/ijch.201600074 %N 8 %0 Journal Article %J Israel Journal of Chemistry %D 2016 %T Solution X‐ray Scattering Form‐Factors with Arbitrary Electron Density Profiles and Polydispersity Distributions %A Ben‐Nun, Tal %A Asor, Roi %A Ginsburg, Avi %A Raviv, Uri %B Israel Journal of Chemistry %I Wiley Online Library %V 56 %P 622-628 %@ 1869-5868 %G eng %U https://onlinelibrary.wiley.com/doi/full/10.1002/ijch.201500037 %N 8 %0 Journal Article %J International journal of molecular sciences %D 2016 %T Spider silk-CBD-cellulose nanocrystal composites: Mechanism of assembly %A Meirovitch, Sigal %A Shtein, Zvi %A Ben-Shalom, Tal %A Lapidot, Shaul %A Tamburu, Carmen %A Hu, Xiao %A Kluge, Jonathan A %A Raviv, Uri %A Kaplan, David L %A Shoseyov, Oded %B International journal of molecular sciences %I Multidisciplinary Digital Publishing Institute %V 17 %P 1573 %G eng %U https://www.mdpi.com/1422-0067/17/9/1573 %N 9 %0 Journal Article %J PLoS One %D 2015 %T Nano-drugs based on nano sterically stabilized liposomes for the treatment of inflammatory neurodegenerative diseases %A Turjeman, Keren %A Bavli, Yaelle %A Kizelsztein, Pablo %A Schilt, Yaelle %A Allon, Nahum %A Katzir, Tamar Blumenfeld %A Sasson, Efrat %A Raviv, Uri %A Ovadia, Haim %A Barenholz, Yechezkel %B PLoS One %I Public Library of Science %V 10 %P e0130442 %@ 1932-6203 %G eng %U https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130442 %N 7 %0 Journal Article %J Proceedings of the National Academy of Sciences %D 2015 %T Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules %A Chung, Peter J %A Choi, Myung Chul %A Miller, Herbert P %A Feinstein, H Eric %A Raviv, Uri %A Li, Youli %A Wilson, Leslie %A Feinstein, Stuart C %A Safinya, Cyrus R %B Proceedings of the National Academy of Sciences %I National Acad Sciences %V 112 %P E6416-E6425 %@ 0027-8424 %G eng %U https://www.pnas.org/content/112/47/E6416.short %N 47 %0 Journal Article %J Nature materials %D 2014 %T Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch %A Ojeda-Lopez, Miguel A %A Needleman, Daniel J %A Song, Chaeyeon %A Ginsburg, Avi %A Kohl, Phillip A %A Li, Youli %A Miller, Herbert P %A Wilson, Leslie %A Raviv, Uri %A Choi, Myung Chul %B Nature materials %I Nature Publishing Group %V 13 %P 195 %@ 1476-4660 %G eng %U https://www.nature.com/articles/nmat3858 %N 2 %0 Book Section %B Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application %D 2014 %T 1 Soft Matter Physics of Lipid Membrane–Based Assemblies %A Harries, Daniel %A Raviv, Uri %B Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application %I CRC Press %P 1 %@ 1466507098 %G eng %U https://books.google.co.il/books?hl=en&lr=&id=XxblAgAAQBAJ&oi=fnd&pg=PA3&dq=info:1YH6gP_7nw8J:scholar.google.com&ots=EsDbAyrnwj&sig=LuXOBjErsKsKXRSSBofT3tRVkrM&redir_esc=y#v=onepage&q&f=false %0 Journal Article %J Nano letters %D 2014 %T Thermal doping by vacancy formation in copper sulfide nanocrystal arrays %A Bekenstein, Yehonadav %A Vinokurov, Kathy %A Keren-Zur, Shay %A Hadar, I %A Schilt, Y %A Raviv, U %A Millo, O %A Banin, U %B Nano letters %I ACS Publications %V 14 %P 1349-1353 %@ 1530-6984 %G eng %U https://pubs.acs.org/doi/abs/10.1021/nl4043642 %N 3 %0 Journal Article %J Macromolecules %D 2014 %T Hierarchical Structures of Polystyrene-block-poly (2-vinylpyridine)/Palladium–Pincer Surfactants: Effect of Weak Surfactant–Polymer Interactions on the Morphological Behavior %A Davidi, Inbal %A Patra, Debabrata %A Hermida-Merino, Daniel %A Portale, Giuseppe %A Rotello, Vincent M %A Raviv, Uri %A Shenhar, Roy %B Macromolecules %I ACS Publications %V 47 %P 5774-5783 %@ 0024-9297 %G eng %U https://pubs.acs.org/doi/abs/10.1021/ma5010343 %N 16 %0 Journal Article %J Langmuir %D 2014 %T Charging and softening, collapse, and crystallization of dipolar phospholipid membranes by aqueous ionic liquid solutions %A Dvir, Tom %A Fink, Lea %A Schilt, Yaelle %A Raviv, Uri %B Langmuir %I ACS Publications %V 30 %P 14725-14733 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la501474r %N 49 %0 Journal Article %J Nucleic acids research %D 2013 %T Effect of capsid confinement on the chromatin organization of the SV40 minichromosome %A Saper, Gadiel %A Kler, Stanislav %A Asor, Roi %A Oppenheim, Ariella %A Raviv, Uri %A Harries, Daniel %B Nucleic acids research %I Oxford University Press %V 41 %P 1569-1580 %@ 1362-4962 %G eng %U https://doi.org/10.1093/nar/gks1270 %N 3 %0 Journal Article %J Soft Matter %D 2013 %T Modulating the structure and interactions of lipid–peptide complexes by varying membrane composition and solution conditions %A Moshe, Leora %A Saper, Gadiel %A Szekely, Or %A Linde, Yaniv %A Gilon, Chaim %A Harries, Daniel %A Raviv, Uri %B Soft Matter %I Royal Society of Chemistry %V 9 %P 7117-7126 %G eng %U https://pubs.rsc.org/en/Content/ArticleLanding/2013/SM/c3sm00105a#!divAbstract %N 29 %0 Journal Article %J Soft Matter %D 2013 %T Charged membranes under confinement induced by polymer-, salt-, or ionic liquid solutions %A Dvir, Tom %A Fink, Lea %A Asor, Roi %A Schilt, Yael %A Steinar, Ariel %A Raviv, Uri %B Soft Matter %I Royal Society of Chemistry %V 9 %P 10640-10649 %G eng %U https://pubs.rsc.org/en/content/articlehtml/2013/sm/c3sm51916c %N 44 %0 Journal Article %J Faraday discussions %D 2013 %T Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules %A Needleman, Daniel J %A Ojeda-Lopez, Miguel A %A Raviv, Uri %A Miller, Herbert P %A Li, Youli %A Song, Chaeyeon %A Feinstein, Stuart C %A Wilson, Leslie %A Choi, Myung Chul %A Safinya, Cyrus R %B Faraday discussions %I Royal Society of Chemistry %V 166 %P 31-45 %G eng %U https://pubs.rsc.org/en/content/articlehtml/2013/fd/c3fd00063j %0 Book Section %B Polymer Adhesion, Friction, and Lubrication %D 2013 %T Polymer brushes and surface forces %A Jacob Klein %A Briscoe, Wuge H %A Chen, Meng %A Eiser, Erika %A Kampf, Nir %A Raviv, Uri %A Tadmor, Rafael %A Tsarkova, Larissa %B Polymer Adhesion, Friction, and Lubrication %I Wiley Online Library %P 135-176 %@ 1118505174 %G eng %U https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118505175.ch4 %0 Book Section %B Polymer Science: A Comprehensive Reference %D 2012 %T Adhesion, friction, and lubrication between polymer-bearing surfaces %A Raviv, U %A Klein, J. %B Polymer Science: A Comprehensive Reference %I Matyjaszewski K. and Möller M. (eds.). Elsevier BV. %C Amsterdam %V 2 %P 607–628 %@ 0080878628 %G eng %0 Journal Article %J Langmuir %D 2012 %T Entropic attraction condenses like-charged interfaces composed of self-assembled molecules %A Steiner, Ariel %A Szekely, Pablo %A Szekely, Or %A Dvir, Tom %A Asor, Roi %A Yuval-Naeh, Naomi %A Keren, Nir %A Kesselman, Ellina %A Danino, Dganit %A Resh, Roy %B Langmuir %I ACS Publications %V 28 %P 2604-2613 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la203540p %N 5 %0 Journal Article %J The Journal of Physical Chemistry B %D 2012 %T Effect of temperature on the interactions between dipolar membranes %A Szekely, Pablo %A Asor, Roi %A Dvir, Tom %A Szekely, Or %A Raviv, Uri %B The Journal of Physical Chemistry B %I ACS Publications %V 116 %P 3519-3524 %@ 1520-6106 %G eng %U https://pubs.acs.org/doi/abs/10.1021/jp209157y %N 11 %0 Journal Article %J Journal of the American Chemical Society %D 2012 %T RNA encapsidation by SV40-derived nanoparticles follows a rapid two-state mechanism %A Kler, Stanislav %A Asor, Roi %A Li, Chenglei %A Ginsburg, Avi %A Harries, Daniel %A Oppenheim, Ariella %A Zlotnick, Adam %A Raviv, Uri %B Journal of the American Chemical Society %I ACS Publications %V 134 %P 8823-8830 %@ 0002-7863 %G eng %U https://pubs.acs.org/doi/abs/10.1021/ja2110703 %N 21 %0 Journal Article %J Journal of controlled release %D 2012 %T Characterization of PEGylated nanoliposomes co-remotely loaded with topotecan and vincristine: relating structure and pharmacokinetics to therapeutic efficacy %A Zucker, Daniel %A Andriyanov, Alexander V %A Steiner, Ariel %A Raviv, Uri %A Barenholz, Yechezkel %B Journal of controlled release %I Elsevier %V 160 %P 281-289 %@ 0168-3659 %G eng %U https://doi.org/10.1016/j.jconrel.2011.10.003 %N 2 %0 Journal Article %J Soft Matter %D 2011 %T Following the structural changes during zinc-induced crystallization of charged membranes using time-resolved solution X-ray scattering %A Nadler, Moshe %A Steiner, Ariel %A Dvir, Tom %A Szekely, Or %A Szekely, Pablo %A Ginsburg, Avi %A Asor, Roi %A Resh, Roy %A Tamburu, Carmen %A Peres, Menahem %B Soft Matter %I Royal Society of Chemistry %V 7 %P 1512-1523 %G eng %U https://pubs.rsc.org/en/content/articlehtml/2011/sm/c0sm00824a %N 4 %0 Journal Article %J Physical Chemistry Chemical Physics %D 2011 %T The dynamic nature of amyloid beta (1–40) aggregation %A Belitzky, Alik %A Melamed-Book, Naomi %A Weiss, Aryeh %A Raviv, Uri %B Physical Chemistry Chemical Physics %I Royal Society of Chemistry %V 13 %P 13809-13814 %G eng %U https://pubs.rsc.org/en/content/articlehtml/2011/cp/c1cp20832b %N 30 %0 Conference Proceedings %B Journal of Physics: Conference Series %D 2011 %T Synchrotron small angle X-ray scattering quantitatively detects angstrom level changes in the average radius of taxol-stabilized microtubules decorated with the microtubule-associated-protein tau %A Choi, Myung Chul %A Raviv, Uri %A Li, Youli %A Miller, Herbert P %A Needleman, Daniel J %A Kim, Mahn Won %A Wilson, Leslie %A Feinstein, Stuart C %A Safinya, Cyrus R %B Journal of Physics: Conference Series %I IOP Publishing %V 272 %P 012001 %@ 1742-6596 %G eng %U https://iopscience.iop.org/article/10.1088/1742-6596/272/1/012001/meta %N 1 %0 Journal Article %J Biochemical and biophysical research communications %D 2011 %T The effect of tachykinin neuropeptides on amyloid β aggregation %A Flashner, Efrat %A Raviv, Uri %A Friedler, Assaf %B Biochemical and biophysical research communications %I Elsevier %V 407 %P 13-17 %@ 0006-291X %G eng %U https://www.sciencedirect.com/science/article/pii/S0006291X11002592 %N 1 %0 Journal Article %J Langmuir %D 2011 %T The structure of ions and zwitterionic lipids regulates the charge of dipolar membranes %A Szekely, Or %A Steiner, Ariel %A Szekely, Pablo %A Einav Amit %A Asor, Roi %A Tamburu, Carmen %A Raviv, Uri %B Langmuir %I ACS Publications %V 27 %P 7419-7438 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la200264s %N 12 %0 Journal Article %J Advanced Materials %D 2011 %T Nanoscale assembly in biological systems: from neuronal cytoskeletal proteins to curvature stabilizing lipids %A Safinya, Cyrus R %A Raviv, Uri %A Needleman, Daniel J %A Zidovska, Alexandra %A Choi, Myung Chul %A Ojeda‐Lopez, Miguel A %A Ewert, Kai K %A Li, Youli %A Miller, Herbert P %A Quispe, Joel %B Advanced Materials %I Wiley Online Library %V 23 %P 2260-2270 %@ 1521-4095 %G eng %U https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201004647 %N 20 %0 Journal Article %J Langmuir %D 2011 %T Regulating the size and stabilization of lipid raft-like domains and using calcium ions as their probe %A Szekely, Or %A Schilt, Yaelle %A Steiner, Ariel %A Raviv, Uri %B Langmuir %I ACS Publications %V 27 %P 14767-14775 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la203074q %N 24 %0 Journal Article %J The Journal of Physical Chemistry B %D 2011 %T Effect of temperature on the structure of charged membranes %A Szekely, Pablo %A Dvir, Tom %A Asor, Roi %A Resh, Roi %A Steiner, Ariel %A Szekely, Or %A Ginsburg, Avi %A Mosenkis, Jonathan %A Guralnick, Vicky %A Dan, Yoav %B The Journal of Physical Chemistry B %I ACS Publications %V 115 %P 14501-14506 %@ 1520-6106 %G eng %U https://pubs.acs.org/doi/abs/10.1021/jp207566n %N 49 %0 Journal Article %J Journal of The Royal Society Interface %D 2011 %T Tilted cellulose arrangement as a novel mechanism for hygroscopic coiling in the stork's bill awn %A Abraham, Yael %A Tamburu, Carmen %A Klein, Eugenia %A Dunlop, John W. C. %A Fratzl, Peter %A Raviv, Uri %A Elbaum, Rivka %B Journal of The Royal Society Interface %I The Royal Society %V 9 %P 640-647 %@ 1742-5689 %G eng %U https://royalsocietypublishing.org/doi/full/10.1098/rsif.2011.0395 %N 69 %0 Journal Article %J Journal of colloid and interface science %D 2010 %T Formation of organic nanoparticles from volatile microemulsions %A Margulis-Goshen, Katrin %A Netivi, Hadas Donio %A Major, Dan T. %A Gradzielski, Michael %A Raviv, Uri %A Magdassi, Shlomo %B Journal of colloid and interface science %I Elsevier %V 342 %P 283-292 %@ 0021-9797 %G eng %U https://www.sciencedirect.com/science/article/pii/S002197970901337X %N 2 %0 Journal Article %J Langmuir %D 2010 %T Solution X-ray scattering form factors of supramolecular self-assembled structures %A Székely, Pablo %A Ginsburg, Avi %A Ben-Nun, Tal %A Raviv, Uri %B Langmuir %I ACS Publications %V 26 %P 13110-13129 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la101433t %N 16 %0 Journal Article %J Colloids and Surfaces A: Physicochemical and Engineering Aspects %D 2010 %T Novaluron nanoparticles: Formation and potential use in controlling agricultural insect pests %A Elek, Naomi %A Hoffman, Roy %A Raviv, Uri %A Resh, Roy %A Ishaaya, Isaac %A Magdassi, Shlomo %B Colloids and Surfaces A: Physicochemical and Engineering Aspects %I Elsevier %V 372 %P 66-72 %@ 0927-7757 %G eng %U https://www.sciencedirect.com/science/article/pii/S0927775710005509 %N 1-3 %0 Journal Article %J Journal of Applied Crystallography %D 2010 %T X+: a comprehensive computationally accelerated structure analysis tool for solution X-ray scattering from supramolecular self-assemblies %A Ben-Nun, Tal %A Ginsburg, Avi %A Székely, Pablo %A Raviv, Uri %B Journal of Applied Crystallography %I International Union of Crystallography %V 43 %P 1522-1531 %@ 0021-8898 %G eng %U https://scripts.iucr.org/cgi-bin/paper?aj5158 %N 6 %0 Journal Article %J The Journal of Physical Chemistry B %D 2009 %T Formation and characterization of ordered bicontinuous microemulsions %A Kogan, Anna %A Shalev, Deborah E. %A Raviv, Uri %A Aserin, Abraham %A Garti, Nissim %B The Journal of Physical Chemistry B %I ACS Publications %V 113 %P 10669-10678 %@ 1520-6106 %G eng %U https://pubs.acs.org/doi/abs/10.1021/jp901617g %N 31 %0 Journal Article %J Biophysical journal %D 2009 %T Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study %A Choi, MC %A Raviv, U %A Miller, HP %A Gaylord, MR %A Kiris, E %A Ventimiglia, D %A Needleman, DJ %A Kim, MW %A Wilson, L %A Feinstein, SC %B Biophysical journal %I Elsevier %V 97 %P 519-527 %@ 0006-3495 %G eng %U https://www.sciencedirect.com/science/article/pii/S0006349509009539 %N 2 %0 Journal Article %J Langmuir %D 2008 %T Normal and frictional forces between surfaces bearing polyelectrolyte brushes %A Raviv, Uri %A Giasson, Suzanne %A Kampf, Nir %A Gohy, Jean-François %A Jérôme, Robert %A Jacob Klein %B Langmuir %I ACS Publications %V 24 %P 8678-8687 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la7039724 %N 16 %0 Journal Article %J Biophysical journal %D 2007 %T Microtubule protofilament number is modulated in a stepwise fashion by the charge density of an enveloping layer %A Raviv, Uri %A Nguyen, Toan %A Ghafouri, Rouzbeh %A Needleman, Daniel J %A Li, Youli %A Miller, Herbert P %A Wilson, Leslie %A Bruinsma, Robijn F %A Safinya, Cyrus R %B Biophysical journal %I Elsevier %V 92 %P 278-287 %@ 0006-3495 %G eng %U https://www.sciencedirect.com/science/article/pii/S0006349507708251 %N 1 %0 Journal Article %J Journal of Applied Crystallography %D 2007 %T Hierarchical bionanotubes formed by the self assembly of microtubules with cationic membranes or polypeptides %A Raviv, Uri %A Needleman, Daniel J %A Ewert, Kai K %A Safinya, Cyrus R %B Journal of Applied Crystallography %I International Union of Crystallography %V 40 %P s83-s87 %@ 0021-8898 %G eng %U http://journals.iucr.org/j/issues/2007/s1/00/sy6014/ %N s1 %0 Journal Article %J Journal of Physics: Condensed Matter %D 2006 %T Cationic membranes complexed with oppositely charged microtubules: hierarchical self-assembly leading to bio-nanotubes %A Raviv, Uri %A Needleman, Daniel J %A Safinya, Cyrus R %B Journal of Physics: Condensed Matter %I IOP Publishing %V 18 %P S1271 %@ 0953-8984 %G eng %U https://iopscience.iop.org/article/10.1088/0953-8984/18/28/S10/meta %N 28 %0 Journal Article %J Langmuir %D 2006 %T Forces between mica surfaces, prepared in different ways, across aqueous and nonaqueous liquids confined to molecularly thin films %A Perkin, Susan %A Liraz Chai %A Kampf, Nir %A Raviv, Uri %A Briscoe, Wuge %A Dunlop, Iain %A Titmuss, Simon %A Seo, Minseok %A Kumacheva, Eugenia %A Jacob Klein %B Langmuir %I ACS Publications %V 22 %P 6142-6152 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la053097h %N 14 %0 Journal Article %J Philosophical Transactions of the Royal Society of London A: Mathematical, Physical and Engineering Sciences %D 2006 %T Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications %A Safinya, Cyrus R %A Ewert, Kai %A Ahmad, Ayesha %A Evans, Heather M %A Raviv, Uri %A Needleman, Daniel J %A Lin, Alison J %A Slack, Nelle L %A George, Cyril %A Samuel, Charles E %B Philosophical Transactions of the Royal Society of London A: Mathematical, Physical and Engineering Sciences %I The Royal Society %V 364 %P 2573-2596 %@ 1364-503X %G eng %U https://royalsocietypublishing.org/doi/full/10.1098/rsta.2006.1841 %N 1847 %0 Journal Article %J Proceedings of the National Academy of Sciences of the United States of America %D 2005 %T Cationic liposome–microtubule complexes: Pathways to the formation of two-state lipid–protein nanotubes with open or closed ends %A Raviv, Uri %A Needleman, Daniel J %A Li, Youli %A Miller, Herbert P %A Wilson, Leslie %A Safinya, Cyrus R %B Proceedings of the National Academy of Sciences of the United States of America %I National Acad Sciences %V 102 %P 11167-11172 %@ 0027-8424 %G eng %U https://www.pnas.org/content/102/32/11167.short %N 32 %0 Journal Article %J Journal of Physics: Condensed Matter %D 2005 %T Supramolecular assembly of biological molecules purified from bovine nerve cells: from microtubule bundles and necklaces to neurofilament networks %A Needleman, Daniel J %A Jones, Jayna B %A Raviv, Uri %A Ojeda-Lopez, Miguel A %A Miller, HP %A Li, Y %A Wilson, L %A Safinya, CR %B Journal of Physics: Condensed Matter %I IOP Publishing %V 17 %P S3225 %@ 0953-8984 %G eng %U https://iopscience.iop.org/article/10.1088/0953-8984/17/45/005/meta %N 45 %0 Journal Article %J Biophysical journal %D 2005 %T Radial compression of microtubules and the mechanism of action of taxol and associated proteins %A Needleman, Daniel J %A Ojeda-Lopez, Miguel A %A Raviv, Uri %A Ewert, Kai %A Miller, Herbert P %A Wilson, Leslie %A Safinya, Cyrus R %B Biophysical journal %I Elsevier %V 89 %P 3410-3423 %@ 0006-3495 %G eng %U https://www.sciencedirect.com/science/article/pii/S0006349505729830 %N 5 %0 Book Section %B Dynamics and friction in Submicrometer confining systems %D 2004 %T The Implication of" Jump-In" for the Shear Viscosity of Ultra Thin Liquid Films %A Raviv, Uri %A Kampf, Nir %A Jacob Klein %B Dynamics and friction in Submicrometer confining systems %I ACS SYMPOSIUM SERIES, Oxford University Press, Washington. Edited by Y. Braiman, J.M. Drake, F. Family & J. Klafter %V 882 %P 131-138 %@ 1947-5918 %G eng %0 Journal Article %J Langmuir %D 2004 %T Fluidity of water confined down to subnanometer films %A Raviv, Uri %A Perkin, Susan %A Laurat, Pierre %A Jacob Klein %B Langmuir %I ACS Publications %V 20 %P 5322-5332 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la030419d %N 13 %0 Journal Article %J Macromolecules %D 2004 %T Normal and shear forces between adsorbed and gelled layers of chitosan, a naturally occurring cationic polyelectrolyte %A Kampf, Nir %A Raviv, Uri %A Jacob Klein %B Macromolecules %I ACS Publications %V 37 %P 1134-1142 %@ 0024-9297 %G eng %U https://pubs.acs.org/doi/abs/10.1021/ma0303263 %N 3 %0 Journal Article %J Physical review letters %D 2004 %T Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: a probe of interprotofilament interactions %A Needleman, Daniel J %A Ojeda-Lopez, Miguel A %A Raviv, Uri %A Ewert, Kai %A Jones, Jayna B %A Miller, Herbert P %A Wilson, Leslie %A Safinya, Cyrus R %B Physical review letters %I APS %V 93 %P 198104 %G eng %U https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.93.198104 %N 19 %0 Journal Article %J Journal of Physics: Condensed Matter %D 2004 %T Fluidity of water and of hydrated ions confined between solid surfaces to molecularly thin films %A Jacob Klein %A Raviv, Uri %A Perkin, Susan %A Kampf, Nir %A Liraz Chai %A Giasson, Suzanne %B Journal of Physics: Condensed Matter %I IOP Publishing %V 16 %P S5437 %@ 0953-8984 %G eng %U https://iopscience.iop.org/article/10.1088/0953-8984/16/45/008/meta %N 45 %0 Journal Article %J Proceedings of the National Academy of Sciences of the United States of America %D 2004 %T Higher-order assembly of microtubules by counterions: from hexagonal bundles to living necklaces %A Needleman, Daniel J %A Ojeda-Lopez, Miguel A %A Raviv, Uri %A Miller, Herbert P %A Wilson, Leslie %A Safinya, Cyrus R %B Proceedings of the National Academy of Sciences of the United States of America %I National Acad Sciences %V 101 %P 16099-16103 %@ 0027-8424 %G eng %U https://www.pnas.org/content/101/46/16099.short %N 46 %0 Journal Article %J Nature %D 2003 %T Lubrication by charged polymers %A Raviv, Uri %A Giasson, Suzanne %A Kampf, Nir %A Gohy, Jean-François %A Jérôme, Robert %A Jacob Klein %B Nature %I Nature Publishing Group %V 425 %P 163 %@ 1476-4687 %G eng %U https://www.nature.com/articles/nature01970 %N 6954 %0 Journal Article %J The Journal of chemical physics %D 2002 %T Time dependence of forces between mica surfaces in water and its relation to the release of surface ions %A Raviv, Uri %A Laurat, Pierre %A Jacob Klein %B The Journal of chemical physics %I AIP %V 116 %P 5167-5172 %@ 0021-9606 %G eng %U https://aip.scitation.org/doi/abs/10.1063/1.1447911 %N 12 %0 Journal Article %J Science %D 2002 %T Fluidity of bound hydration layers %A Raviv, Uri %A Jacob Klein %B Science %I American Association for the Advancement of Science %V 297 %P 1540-1543 %@ 0036-8075 %G eng %U http://science.sciencemag.org/content/297/5586/1540 %N 5586 %0 Journal Article %J Journal of Physics: Condensed Matter %D 2002 %T Viscosity of ultra-thin water films confined between hydrophobic or hydrophilic surfaces %A Raviv, Uri %A Giasson, Suzanne %A Frey, Joseph %A Jacob Klein %B Journal of Physics: Condensed Matter %I IOP Publishing %V 14 %P 9275 %@ 0953-8984 %G eng %U https://iopscience.iop.org/article/10.1088/0953-8984/14/40/317/meta %N 40 %0 Journal Article %J Langmuir %D 2002 %T Properties and interactions of physigrafted end-functionalized poly (ethylene glycol) layers %A Raviv, Uri %A Frey, Joseph %A Sak, Rinat %A Laurat, Pierre %A Tadmor, Rafael %A Jacob Klein %B Langmuir %I ACS Publications %V 18 %P 7482-7495 %@ 0743-7463 %G eng %U https://pubs.acs.org/doi/abs/10.1021/la020002s %N 20 %0 Journal Article %J Polymers for Advanced Technologies %D 2002 %T Healing of adsorbed polymer layers in a narrow gap following removal by shear %A Raviv, Uri %A Jacob Klein %B Polymers for Advanced Technologies %I Wiley Online Library %V 13 %P 1032-1038 %@ 1099-1581 %G eng %U https://onlinelibrary.wiley.com/doi/abs/10.1002/pat.236 %N 10‐12 %0 Journal Article %J The European Physical Journal E %D 2002 %T The polymer mat: Arrested rebound of a compressed polymer layer %A Raviv, Uri %A Jacob Klein %A Witten, TA %B The European Physical Journal E %I Springer %V 9 %P 405-412 %@ 1292-8941 %G eng %U https://link.springer.com/article/10.1140/epje/i2002-10053-9 %N 1 %0 Journal Article %J The European Physical Journal E: Soft Matter and Biological Physics %D 2002 %T Raviv et al. respond %A Raviv, U %A Klein, J. %A Witten, TA %B The European Physical Journal E: Soft Matter and Biological Physics %I Springer %V 9 %P 425-426 %@ 1292-8941 %G eng %U https://link.springer.com/article/10.1140%2Fepje%2Fi2003-10004-0?LI=true %N 5 %0 Journal Article %J The Journal of Physical Chemistry B %D 2001 %T Shear and frictional interactions between adsorbed polymer layers in a good solvent %A Raviv, Uri %A Tadmor, Rafael %A Jacob Klein %B The Journal of Physical Chemistry B %I ACS Publications %V 105 %P 8125-8134 %@ 1520-6106 %G eng %U https://pubs.acs.org/doi/abs/10.1021/jp0041860 %N 34 %0 Journal Article %J Nature %D 2001 %T Fluidity of water confined to subnanometre films %A Raviv, Uri %A Laurat, Pierre %A Jacob Klein %B Nature %I Nature Publishing Group %V 413 %P 51 %@ 1476-4687 %G eng %U https://www.nature.com/articles/35092523 %N 6851