Publications

2020
Khaykelson D, Raviv U. Studying viruses using solution X-ray scattering. Biophysical Reviews [Internet]. 2020;12 :41–48. Publisher's VersionAbstract

Viruses have been of interest to mankind since their discovery as small infectious agents in the nineteenth century. Because many viruses cause diseases to humans and agriculture, they were rigorously studied for biological and medical purposes. Viruses have remarkable properties such as the symmetry and self-assembly of their protein envelope, maturation into infectious virions, structural stability, and disassembly. Solution X-ray scattering can probe structures and reactions in solutions, down to subnanometer spatial resolution and millisecond temporal resolution. It probes the bulk solution and reveals the average shape and average mass of particles in solution and can be used to study kinetics and thermodynamics of viruses at different stages of their life cycle. Here we review recent work that demonstrates the capabilities of solution X-ray scattering to study in vitro the viral life cycle.

2019
Dharan R, Shemesh A, Millgram A, Levi-Kalisman Y, Ringel I, Raviv U. Hierarchical Assembly Pathways of Spermine Induced Tubulin Conical-Spiral Architectures. [Internet]. 2019. Publisher's Version
Shaltiel L, Shemesh A, Raviv U, Barenholz Y, Levi-Kalisman Y. Synthesis and Characterization of Thiolate-Protected Gold Nanoparticles of Controlled Diameter. J. Phys. Chem. C [Internet]. 2019;123 (46) :28486-28493. Publisher's Version
Safinya CR, Chung PJ, Song C, Li Y, Miller HP, Choi MC, Raviv U, Ewert KK, Wilson L, Feinstein SC. Minireview-Microtubule and Tubulin Oligomers: Shape Transitions and Assembly by Intrinsically Disordered Protein Tau and Cationic Biomolecules. Langmuir [Internet]. 2019;35 (48) :15970–15978. Publisher's Version
Fink L, Steiner A, Szekely O, Szekely P, Raviv U. Structure and Interactions between Charged Lipid Membranes in the Presence of Multivalent Ions. Langmuir [Internet]. 2019;35 (30) :9694-9703. Publisher's Version
Asor R, Selzer L, Schlicksup CJ, Zhao Z, Zlotnick A, Raviv U. Assembly Reactions of Hepatitis B Capsid Protein into Capsid Nanoparticles Follow a Narrow Path Through a Complex Reaction Landscape. ACS Nano [Internet]. 2019;13 (7) :7610-7626. Publisher's Version
Zhao Z, Che-Yen Wang J, Gonzalez-Gutierrez G, Venkatakrishnan B, Asor R, Khaykelson D, Raviv U, Zlotnick A. Structural differences between the Woodchuck hepatitis virus core protein in dimer and capsid states are consistent with entropic and conformational regulation of assembly. Journal of Virology [Internet]. 2019 :JVI.00141-19. Publisher's Version
Ginsburg A, Ben-Nun T, Asor R, Shemesh A, Fink L, Tekoah R, Levartovsky Y, Khaykelson D, Dharan R, Fellig A, et al. D+: software for high-resolution hierarchical modeling of solution X-ray scattering from complex structures. Journal of Applied Crystallography [Internet]. 2019;52 (1) :219-242. Publisher's Version
Asor R, Khaykelson D, Ben-nun-Shaul O, Oppenheim A, Raviv U. Effect of Calcium Ions and Disulfide Bonds on Swelling of Virus Particles. ACS Omega [Internet]. 2019;4 (1) :58–64. Publisher's Version
Aviv Y, Altay E, Fink L, Raviv U, Rzayev J, Shenhar R. Quasi-Two-Dimensional Assembly of Bottlebrush Block Copolymers with Nanoparticles in Ultrathin Films: Combined Effect of Graft Asymmetry and Nanoparticle Size. Macromolecules [Internet]. 2019;52 (1) :196-207. Publisher's Version
2018
Levartovsky Y, Shemesh A, Asor R, Raviv U. Effect of Weakly Interacting Cosolutes on Lysozyme Conformations. ACS Omega [Internet]. 2018;3 (11) :16246–16252. Publisher's Version
Shemesh A, Ginsburg A, Levi-Kalisman Y, Ringel I, Raviv U. Structure, Assembly, and Disassembly of Tubulin Single Rings. Biochemistry [Internet]. 2018;57 (43) :6153-6165. Publisher's Version
Cohen E, Soffer Y, Weissman H, Bendikov T, Schilt Y, Raviv U, Rybtchinski B. Hydrophobicity Control in Adaptive Crystalline Assemblies. Angewandte Chemie [Internet]. 2018;130 (29) :9009-9012. Publisher's Version
Raviv U. Interacting Bacteria Surfaces. Biophysical journal [Internet]. 2018;114 (7) :1515-1517. Publisher's Version
2017
Louzon D, Ginsburg A, Schwenger W, Dvir T, Dogic Z, Raviv U. Structure and Intermolecular Interactions between L-Type Straight Flagellar Filaments. Biophysical journal [Internet]. 2017;112 (10) :2184-2195. Publisher's Version
Chung PJ, Song C, Miller HP, Li Y, Raviv U, Choi MC, Wilson L, Feinstein SC, Safinya CR. Synchrotron small-angle X-ray scattering and electron microscopy characterization of structures and forces in microtubule/Tau mixtures. In: Methods in cell biology. Vol. 141. Academic Press ; 2017. pp. 155-178. Publisher's Version
Eyal LB, Choubeh RR, Cohen E, Eisenberg I, Tamburu C, Dorogi M, Ünnep R, Appavou M-S, Nevo R, Raviv U, et al. Changes in aggregation states of light-harvesting complexes as a mechanism for modulating energy transfer in desert crust cyanobacteria. Proceedings of the National Academy of Sciences [Internet]. 2017;114 (35) :9481-9486. Publisher's Version
Fink L, Feitelson J, Noff R, Dvir T, Tamburu C, Raviv U. Osmotic stress induced desorption of calcium ions from dipolar lipid membranes. Langmuir [Internet]. 2017;33 (23) :5636-5641. Publisher's Version
Ginsburg A, Shemesh A, Millgram A, Dharan R, Levi-Kalisman Y, Ringel I, Raviv U. Structure of Dynamic, Taxol-Stabilized, and GMPPCP-Stabilized Microtubule. The Journal of Physical Chemistry B [Internet]. 2017;121 (36) :8427-8436. Publisher's Version
Eisenberg I, Harris D, Levi-Kalisman Y, Yochelis S, Shemesh A, Ben-Nissan G, Sharon M, Raviv U, Adir N, Keren N. Concentration-based self-assembly of phycocyanin. Photosynthesis research [Internet]. 2017;134 (1) :39-49. Publisher's Version

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