Publications

2018
Naim R, Kivity Y, Bar-Haim Y, Huppert JD. Attention and interpretation bias modification treatment for social anxiety disorder: A randomized clinical trial of efficacy and synergy. Journal of Behavior Therapy and Experimental Psychiatry [Internet]. 2018;59 :19 - 30. Publisher's VersionAbstract
Background and objectives Attention bias modification treatment (ABMT) and cognitive bias modification of interpretation (CBM-I) both have demonstrated efficacy in alleviating social anxiety, but how they compare with each other, their combination, and with a combined control condition has not been studied. We examined their relative and combined efficacy compared to control conditions in a randomized controlled trial (RCT).
2017
Sugarman MA, Kirsch I, Huppert JD. Obsessive-compulsive disorder has a reduced placebo (and antidepressant) response compared to other anxiety disorders: A meta-analysis. Journal of Affective Disorders [Internet]. 2017 :217. Publisher's VersionAbstract
Previous studies have indicated that obsessive-compulsive disorder (OCD) might have a reduced placebo response compared to other anxiety-related disorders including generalized anxiety disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder. No previous analysis has directly compared antidepressant and placebo responses between OCD and these conditions.
Siev J, Abramovitch A, Ogen G, Burstein A, Halaj A, Huppert JD. Religion, moral thought–action fusion, and obsessive–compulsive features in Israeli Muslims and Jews. Mental Health, Religion & Culture [Internet]. 2017;20 (7) :696 - 707. Publisher's VersionAbstract
Previous studies suggest that the link between obsessive–compulsive (OC) symptoms and moral thought–action fusion (TAF) depends on religion; however, no study has compared Muslim and Jewish samples. We examined the relationships between OC symptoms, scrupulosity, religiosity, and moral TAF in Israeli Muslims and Jews. Religiosity was not associated with elevations in OC symptoms, although religiosity correlated with scrupulosity across the entire sample after controlling for depression and anxiety. Moral TAF was related to scrupulosity across the entire sample. The Muslim group had higher levels of OC symptoms, scrupulosity, and depressive symptoms than did the Jewish group, but the groups were equally religious. In addition, Muslims scored higher than did Jews on moral TAF even after controlling for symptoms; however, moral TAF was not related to scrupulosity within the Muslim group. In combination, these results imply that moral TAF depends on cultural and religious factors and does
Sugarman MA, Kirsch I, Huppert JD. Review article: Obsessive-compulsive disorder has a reduced placebo (and antidepressant) response compared to other anxiety disorders: A meta-analysis. Journal of Affective Disorders [Internet]. 2017;218 :217 - 226. Publisher's VersionAbstract
Background Previous studies have indicated that obsessive-compulsive disorder (OCD) might have a reduced placebo response compared to other anxiety-related disorders including generalized anxiety disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder. No previous analysis has directly compared antidepressant and placebo responses between OCD and these conditions.
2016
Kivity Y, Huppert JD. Does cognitive reappraisal reduce anxiety? A daily diary study of a micro-intervention with individuals with high social anxiety. Journal of Consulting and Clinical Psychology [Internet]. 2016;(3) :269. Publisher's VersionAbstract
Objective: To examine emotion regulation (ER) among individuals with high (HSA) and low social anxiety (LSA) and the effects of 1 week of practiced cognitive reappraisal using self-report, daily diary measures and lab tasks. Method: HSAs received reappraisal (HSA-R; n = 43) or monitoring (HSA-M; n = 40) instructions. LSAs received monitoring instructions (LSA-M; n = 41). Self-report measures of social anxiety and ER, and a lab task of reappraisal were administered at baseline and after 1 week. Daily diaries of anxiety and ER were also collected. Results: At baseline, HSAs compared with LSAs reported lower self-efficacy of reappraisal and higher frequency and self-efficacy of suppression, but no differences emerged in the reappraisal task. Following the intervention, the HSA-R compared with the HSA-M reported lower symptom severity, greater self-efficacy of reappraisal but equal daily anxiety. HSA-R used reappraisal mostly combined with suppression (74.76% of situations). Post hoc anal
Rodebaugh TL, Scullin RB, Langer JK, Dixon DJ, Huppert JD, Bernstein A, Zvielli A, Lenze EJ. Unreliability as a threat to understanding psychopathology: the cautionary tale of attentional bias. Journal of Abnormal Psychology [Internet]. 2016;(6) :840. Publisher's VersionAbstract
In the original article, there was an error in the Author Note. It incorrectly stated, oDevelopment of the MacBrain Face Stimulus Set was overseen by Nim Tottenham and supported by the Jonathan D. Huppert and Catherine T. MacArthur Foundation Research Network on Early Experience and Brain Development.o It should have stated, oDevelopment of the MacBrain Face Stimulus Set was overseen by Nim Tottenham and supported by the John D. and Catherine T. MacArthur Foundation Research Network on Early Experience and Brain Development.o The online version of this article has been corrected.] The use of unreliable measures constitutes a threat to our understanding of psychopathology, because advancement of science using both behavioral and biologically oriented measures can only be certain if such measurements are reliable. Two pillars of the National Institute of Mental HealthEs portfoliouthe Research Domain Criteria (RDoC) initiative for psychopathology and the target engagement initiative in c
2015
Nacasch N, Huppert JD, Su Y-J, Kivity Y, Dinshtein Y, Yeh R, Foa EB. Are 60-Minute Prolonged Exposure Sessions With 20-Minute Imaginal Exposure to Traumatic Memories Sufficient to Successfully Treat PTSD? A Randomized Noninferiority Clinical Trial. Behavior Therapy [Internet]. 2015;46 :328 - 341. Publisher's VersionAbstract
The study aims to determine whether 60-minute sessions of prolonged exposure (PE) that include 20minutes of imaginal exposure (IE) are noninferior to the standard 90-minute sessions that include 40minutes of IE in treating posttraumatic stress disorder (PTSD) and to explore the relationship of treatment outcome to within- and between-session habituation and change in negative cognitions. Thirty-nine adult veterans with chronic PTSD were randomly assigned to 90-minute (n=19) or 60-minute (n=20) sessions of PE. PTSD symptoms were assessed by an unaware independent evaluator before and after treatment and at 6-month follow-up. Self-reports of depression and negative cognitions were assessed before and after treatment. Participants in both conditions showed significant reductions in PTSD symptoms. Sixty-minute sessions were found to be noninferior to 90-minute sessions in reducing PTSD symptoms, as the upper bound of the 95% confidence interval for the difference between conditions in the
Foa EB, Simpson HB, Rosenfield D, Liebowitz MR, Cahill SP, Huppert JD, Bender J, McLean CP, Maher MJ, Campeas R, et al. Six-Month Outcomes from a Randomized Trial Augmenting Serotonin Reuptake Inhibitors with Exposure and Ritual Prevention or Risperidone in Adults with Obsessive-Compulsive Disorder. [Internet]. 2015. Publisher's Version
2014
Huppert JD. Maximizing the potential of psychology for the Israeli mental health reform. [Internet]. 2014. Publisher's VersionAbstract
The author comments on Nirel and Samuel’s article showing that psychologists in Israel reported practicing inconsistently with the likely demands of an upcoming Israel mental health reform. Some of the reasons for the differences in preparedness between psychologists and psychiatrists are considered. In addition, incorporating the knowledge from psychology to improve access, assessment, treatment and training in Israel is discussed as a way to help both the reform and psychologists advance treatments in Israel. Finally, a suggestion for 21st century models of service delivery is suggested. [...]
2013
Aderka IM, McLean CP, Huppert JD, Davidson JRT, Foa EB. Fear, avoidance and physiological symptoms during cognitive-behavioral therapy for social anxiety disorder. Behaviour Research and Therapy [Internet]. 2013;51 :352 - 358. Publisher's VersionAbstract
We examined fear, avoidance and physiological symptoms during cognitive-behavioral therapy (CBT) for social anxiety disorder (SAD). Participants were 177 individuals with generalized SAD who underwent a 14-week group CBT as part of a randomized controlled treatment trial. Participants filled out self-report measures of SAD symptoms at pre-treatment, week 4 of treatment, week 8 of treatment, and week 14 of treatment (post-treatment). Cross-lagged Structural Equation Modeling indicated that during the first 8 weeks of treatment avoidance predicted subsequent fear above and beyond previous fear, but fear did not predict subsequent avoidance beyond previous avoidance. However, during the last 6 weeks of treatment both fear and avoidance predicted changes in each other. In addition, changes in physiological symptoms occurred independently of changes in fear and avoidance. Our findings suggest that changes in avoidance spark the cycle of change in treatment of SAD, but the cycle may continu
Huppert JD, Kivity Y, Barlow DH, Gorman JM, Shear MK, Woods SW. Therapist effects and the outcome—alliance correlation in cognitive behavioral therapy for panic disorder with agoraphobia. [Internet]. 2013. Publisher's VersionAbstract
Although the alliance–outcome correlation is well established, no published studies to date have separated between therapists’ and patients’ contributions while controlling for early symptom change. In this study, we examined therapist effects in two trials of CBT for panic disorder with agoraphobia (PDA) and the impact of therapists’ and patients’ contribution to the alliance on outcome and attrition in one trial. Alliance ratings were obtained from patients and therapists early and late in treatment (n = 133). Data were analyzed using multi-level modeling controlling for early symptom change. No therapist effects were found. The patients’ contribution to the alliance predicted [...]
Aderka IM, McLean CP, Huppert JD, Davidson JRT, Foa EB. Fear, Avoidance and Physiological Symptoms during Cognitive-Behavioral Therapy for Social Anxiety Disorder. [Internet]. 2013. Publisher's VersionAbstract
We examined fear, avoidance and physiological symptoms during cognitive-behavioral therapy (CBT) for social anxiety disorder (SAD). Participants were 177 individuals with generalized SAD who underwent a 14-week group CBT as part of a randomized controlled treatment trial. Participants filled out self-report measures of SAD symptoms at pre-treatment, week 4 of treatment, week 8 of treatment, and week 14 of treatment (post-treatment). Cross-lagged Structural Equation Modeling indicated that during the first 8 weeks of treatment avoidance predicted subsequent fear above and beyond previous fear, but fear did not predict subsequent avoidance beyond previous avoidance. However, during the last 6 weeks of [...]