Citation:
Simaan, S. ; Masarwa, A. ; Bertus, P. ; Marek*, I. Enantiomercally Pure Cyclopropeneylecarbenols as a Source of Chiral Alkylidenecyclopropane Derivatives. Angew. Chem., Int. Ed. 2006, 45, 3963-3965.
Abstract:
The straightforward approach: The copper-catalyzed carbomagnesiation reaction of chiral cyclopropenylcarbinol derivatives, obtained through kinetic resolution of secondary allylic alcohols, leads to the preparation of enantiomerically pure alkylidenecyclopropane derivatives. The reaction mechanism is composed of a syn carbometalation followed by a syn elimination reaction.