Publications

2017

Rimmerman R., Schottlender N, Reshef R, Dan-Goor N, Yirmiya R. The hippocampal transcriptomic signature of stress resilience in mice with microglial fractalkine receptor (CX3CR1) deficiency. Brain Behavior and Immunity, 61: 184-196, 2017. [Link]

2016

Walker FR, Yirmiya R. Microglia, physiology and behavior: A brief commentary. Brain Behavior and Immunity. 55: 1-5, 2016.

Yirmiya R, Walker FR (Eds.). Microglia, Physiology and Behavior. Special Issue Published in Brain, Behavior and Immunity, 2016.

2015

Yirmiya R, Rimmerman N, Reshef R. Depression as a Microglial Disease. Trends in Neurosciences, 38(10): 637-58, 2015. [Link]

2014

Ben Menachem Zidon O, Ben Menahem Y, Ben Hur T, Yirmiya R. Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer's disease model. Neuropsychopharmacology, 39(2):401-414, 2014. [Link]

Fleshner M, Greenwood BN, Yirmiya R. Neuronal-Glial Mechanisms of Exercise-Evoked Stress Robustness. Curr Top Behav Neurosci. 18: 1-12, 2014. [Link]

Kreisel T, Frank MG, Licht T, Reshef R, Ben-Menachem-Zidon O, Baratta MV, Maier SF, Yirmiya R. Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis. Molecular Psychiatry. 19(6):699-709, 2014. [Link]

Reshef R, Kreisel T, Beroukhim Kay D, Yirmiya R. Microglia and their CX3CR1 signaling are involved in hippocampal- but not olfactory bulb-related memory and neurogenesis. Brain Behavior and Immunity. 41: 239-50, 2014. [Link]

2013

Bab I, Yirmiya R. Neuropsychiatric Disorders and the Skeleton. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition. Edited by Clifford J. Rosen. John Wiley & Sons, Inc. 2013, pp. 1002-1011.

2012

Bajayo A, Bar A, Denes A, Bachar M, Kram V, Attar-Namdar M, Zallone A, Kovács KJ, Yirmiya R, Bab I. Skeletal parasympathetic innervation communicates central IL-1 signals regulating bone mass accrual. Proc Natl Acad Sci USA. 109(38):15455-15460, 2012. [Link]

Maes M, Song C, Yirmiya R. Targeting IL-1 in depression. Expert Opinion on Therapeutic Targets. 16(11):1097-112, 2012. [Link]

2011

Ben Menachem-Zidon O, Avital A, Ben-Menahem Y, Goshen I, Kreisel T, Shmueli EM, Segal M, Ben Hur T, Yirmiya R. Astrocytes support hippocampal-dependent memory and long-term potentiation via interleukin-1 signaling. Brain Behavior and Immunity. 25:1008-16, 2011. [Link]

Gabay, E, Wolf G, Shavit Y, Yirmiya R, Tal M. Chronic blockade of interleukin-1 (IL-1) prevents and attenuates neuropathic pain behavior and spontaneous ectopic neuronal activity following nerve injury. Eur J Pain, 15(3):242-248, 2011. [Link]

Licht T, Goshen I, Avital A, Kreisel T, Zubedat S, Eavri R, Segal M, Yirmiya R, Keshet E. Reversible modulations of neuronal plasticity by VEGF. Proc Natl Acad Sci U S A. 108(12):5081-5086, 2011. [Link]

Yirmiya R, Goshen I. Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behavior and Immunity, 25(2):181-213, 2011. [Link]

2010

Bab I, Yirmiya R. Depression and bone mass. Ann NY Acad Sci., 1192:170-175, 2010. [Link]

Bab I, Yirmiya R. Depression, selective serotonin reuptake inhibitors, and osteoporosis. Current Osteoporosis Reports, 8(4):185-191, 2010.  [Link]

2009

Bab I, Yirmiya R. Depression, selective serotonin re-uptake inhibitors and the regulation of bone mass. IBMS BoneKEy, 6(1):8-15, 2009. [Link]

Goshen I, Avital A, Kreisel T, Licht T, Segal M, Yirmiya R. Environmental enrichment restores memory functioning in mice with impaired IL-1 signaling via reinstatement of long term potentiation and spine size enlargement. Journal of Neuroscience, 29:3395-340, 2009. [Link]

Goshen I, Yirmiya R. Interleukin-1 (IL-1): A central regulator of stress responses. Frontiers in Neuroendocrinology, 30(1):30-45, 2009. [Link]

Goshen I, Yirmiya R. The role of proinflammatory cytokines in memory processes and neural plasticity. In: Ader, R. (Ed.) Psychoneuroimmunology, 4th Editions. pp. 337-377, Elsevier Inc.: Amsterdam, 2007. [Link]

Goshen, I. and Yirmiya, R. Brain interleukin-1 (IL-1) mediates stress-induced alterations in HPA activation, memory functioning and neural plasticity. In: Soreq, H., Kaufer, D. and Friedman, A. Stress: from molecules to behaviour. A comprehensive analysis of the neurobiology of stress responses. Wiley Publishing, 2009.

Maes M, Yirmyia R, Noraberg J, Brene S, Hibbeln J, Perini G, Kubera M, Bob P, Lerer B, Maj M. The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression. Metabolic Brain Diseases. 24(1):27-53, 2009. [Link]

Ounallah-Saad H, Beeri R, Goshen I, Yirmiya R, Renbaum P, Levy-Lahad E. Transcriptional regulation of the murine Presenilin-2 gene reveals similarities and differences to its human orthologue. Gene, 446:81-89, 2009. [Link]

Shavit Y, Wolf G, Johnston IN, Westbrook FR, Watkins LR, Yirmiya R. Proinflammatory cytokines modulate neuropathic pain, opioid analgesia, and opioid tolerance. In: DeLeo J., Sorkin L., and Watkins L. (Eds.), Immune and Glial Regulation of Pain. IASP Press, Seattle, 2007, pp. 361-382.

Yirmiya R, Bab I. Major depression is a risk factor for low bone mineral density: A meta-analysis. Biological Psychiatry, 66:423-432, 2009.[Link]

Yirmiya, R. The inflammatory nature of depression. Frontiers in Neuroscience. 3: 262, 2009.

2008

Ben Menachem- Zidon O, Goshen I, Kreisel T, Ben Menahem Y, Reinhartz E, Ben Hur T, Yirmiya R. Intrahippocampal transplantation of transgenic neural precursor cells over-expressing interleukin-1 receptor antagonist blocks chronic stress-induced impairment in memory and neurogenesis. Neuropsychopharmacology, 33(9):2251-62, 2008. [Link]

Bilbo SD, Yirmiya R, Amat J, Paul ED, Watkins LR, Maier SF. Bacterial infection early in life protects against stressor-induced depressive-like symptoms in adult rats. Psychoneuroendocrinology, 33(3):261-269, 2008. [Link]

Christianson JP, Paul ED, Irani M, Thompson BM, Kubala KH, Yirmiya R, Watkins LR, Maier SF. The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration. Behavioral Brain Research, 193(1):87-93, 2008. [Link]

Dantzer R, Capuron L, Irwin MR, Miller AH, Ollat H, Perry VH, Rousey S, Yirmiya R. Identification and treatment of symptoms associated with inflammation in medically ill patients. Psychoneuroendocrinology, 33:18-29, 2008. [Link]

Goshen I, Kreisel T, Ben-Menachem-Zidon O, Weidenfeld J, Ben-Hur T, Yirmiya R. Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Molecular Psychiatry, 13(7):717-728, 2008. [Link]

Kleibeuker W, Gabay E, Kavelaars A, Zijlstra J, Wolf G, Ziv N, Yirmiya R, Shavit Y, Tal M, Heijnen CJ.  IL-1β signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2.  Brain, Behavior, and Immunity, 22:200-208, 2008. [Link]

Shapira-Lichter I, Beilin B, Ofek K, Bessler H, Ballas M, Shavit Y, Seror D, Grinevich G, Posner E, Reichenberg A, Soreq H, Yirmiya R. Cytokines and cholinergic signals co-modulate surgery stress-induced changes in mood and memory. Brain, Behavior, and Immunity, 22(3):388-398, 2008. [Link]

Tam J, Trembovler V, Di Marzo V, Petrosino S, Leo G, Alexandrovich A, Regev E, Casap N, Shteyer A, Ledent C, Karsak M, Zimmer A, Mechoulam R, Yirmiya R, Shohami E, Bab I. The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. FASEB Journal, 22:285-294, 2008. [Link]

Wolf G, Livshits D, Beilin B, Yirmiya R, Shavit Y. Interleukin-1 signaling is required for induction and maintenance of postoperative incisional pain: genetic and pharmacological studies in mice. Brain, Behavior, and Immunity, 22(7):1072-1077, 2008. [Link]

2007

Bener D, Wohlman A, Itzik A, Yirmiya R, Ben-Hur T, Weidenfeld J. Glucocorticoid Resistance following Herpes Simplex-1 Infection: Role of Hippocampal Glucocorticoid Receptors. Neuroendocrinology, 85(4):207-215, 2007. [Link]

Goshen I, Kreisel T, Ounallah-Saad H, Zalzstein Y, Ben-Hur T, Levy-Lahad E, Yirmiya R. A dual role for interleukin-1 in hippocampal-dependent memory processes. Psychoneuroendocrinology, 32: 1106-1115, 2007. [Link]

Goshen I, Yirmiya R. The role of proinflammatory cytokines in memory processes and neural plasticity. In  Ader R (Ed.), Psychoneuroimmunology, 4th Editions. pp. 337-377, Elsevier Inc.: Amsterdam, 2007. [Link]

Ofek K, Krabbe KS, Evron T, Debecco M, Nielsen AR, Brunnsgaad H, Yirmiya R., Soreq H, Pedersen BK. Cholinergic status modulations in human volunteers under acute inflammation. Journal of Molecular Medicine, 85: 1239-1251, 2007. [Link]

Wolf G, Yirmiya R, Kreisel T, Goshen I, Weidenfeld J, Poole S, Shavit Y. Interleukin-1 signaling modulates stress-induced analgesia. Brain, Behavior, and Immunity, 21(5):652-9, 2007. [Link]

2006

Goldstein I, Levy T, Galili D, Ovadia H, Yirmiya R, Rosen H, Lichtstein D. Involvement of Na(+), K(+)-ATPase and Endogenous Digitalis-Like Compounds in Depressive Disorders. Biological Psychiatry, 60(5):491-499, 2006. [Link]

Taylor, A.N., Chiappelli, F., Tritt, S.H., Yirmiya, R., Romeo, H.E. Fetal alcohol syndrome, fetal, alcohol exposure and neuro-endocrine-immune interactions. Clin. Neurosci. Res. 6(1-2): 42-51, 2006. [Link]

Wolf G, Gabay E, Tal M, Yirmiya R, Shavit Y. Genetic impairment of interleukin-1 signaling attenuates neuropathic pain, autotomy, and spontaneous ectopic neuronal activity, following nerve injury in mice. Pain, 120 (3): 315-324, 2006. [Link]

Yirmiya R, Goshen I, Bajayo A, Kreisel T, Feldman S, Tam J, Trembovler V, Csernus V, Shohami E, Bab I. Depression induces bone loss through stimulation of the sympathetic nervous system. Proc Natl Acad Sci USA,103(45):16876-16881, 2006. And see Research Highlights, Nature Medicine, 12 (12): 1362, 2006. [Link]

2005

Bajayo A, Goshen I, Feldman S, Csernus V, Iverfeldt K, Shohami E, Yirmiya R, Bab I. Central IL-1 receptor signaling regulates bone growth and mass. Proc Natl Acad Sci USA, 102:12956-12961, 2005. [Link]

Hurwitz I, Malkesman O, Stern Y, Schroeder M, Lavi-Avnon Y, Shayit M, Shavit Y, Wolf G, Yirmiya R, Weller A. Stress and pain responses in rats lacking CCK(1) receptors. Peptides. 27(6):1483-1489, 2005. [Link]

Krabbe KS, Reichenberg A, Yirmiya R, Smed A, Pedersen BK, Bruunsgaard H. Low-dose endotoxemia and human neuropsychological functions. Brain Behavior and Immunity, 19:453-460, 2005. [Link]

Pollak Y, Gilboa A, Ben-Menachem O, Ben-Hur T, Soreq H, Yirmiya R. Acetylcholinesterase modulates interleukin-1β production in the hippocampus and blood. Annals of Neurology, 57:741-745, 2005. [Link]

Shavit Y, Wolf G, Goshen I, Livshits D, Yirmiya R. Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance. Pain, 115(1-2):50-59, 2005. [Link]

Shavit Y, Fisch G, Wolf G, Mayburd E, Meerson Y, Yirmiya R, Beilin B. The Effects of Perioperative Pain Management Techniques on Food Consumption and Body Weight Following Laparotomy in Rats. Anesthesia & Analgesia, 101(4):1112-1116, 2005. [Link]

Soreq H, Yirmiya R, Cohen O, Glick D. Acetylcholinesterase as a window onto stress responses. In:  T. Steckler, N. Kalin, and J.M.H.M. Reul (Eds.), Handbook on Stress, Immunology and Behaviour. pp. 585-607, Elsevier Science: Amsterdam, 2005. [Link]

Taylor AN, Tritt DH, Yirmiya R, Chiappelli F. Maternal alcohol consumption and neuroendocrine-immune interactions in the offspring. In: D.M. Hodgson & C. Coe, (Eds):  Perinatal Programming:  Early Life Determinants of Adult Health & Disease, Taylor & Francis Medical Books: London, UK, 2005.

Weidenfeld J, Itzik A, Goshen I, Yirmiya R, Ben-Hur T. Role of the central amygdala in modulating the pituitary-adrenocortical and clinical responses in experimental herpes simplex virus-1 encephalitis. Neuroendocrinology, 81:267-272, 2005. [Link]

2004

Ben-Hur T, Itzik A, Barak O, Asher Y, Becker Y, Yirmiya R, Weidenfeld J. Immunization with a nonpathogenic HSV-1 strain prevents clinical and neuroendocrine changes of experimental HSV-1 encephalitis. Journal of Neuroimmunology, 152: 5-10, 2004. [Link]

2003

Avital A, Goshen I, Kamseler A, Segal M, Iverfeldt K, Richter-Levin G, Yirmiya R. Impaired interleukin-1 (IL-1) signaling is associated with defects in neural plasticity and memory processes. Hippocampus, 13: 826-834, 2003. [Link]

Cohen O, Reichenberg A, Perry C, Ginzberg D, Pollmächer T, Soreq H, Yirmiya R. Endotoxin-induced changes in human working and declarative memory is associated with cleavage of plasma “readthrough”  acetylcholinesterase. Journal of Molecular Neuroscience, 21: 199-212, 2003. [Link]

Goshen I, Yirmiya R, Iverfeldt K, Weidenfeld J. The role of endogenous inerleukin-1 in HPA axis activation following stress or adrenalectomy. Endocrinology, 144: 4453-4458, 2003. [Link]

Pollak Y, Ovadia H, Orion E, Weidenfeld J, Yirmiya R. The EAE-associated behavioral syndrome: I. Temporal correlation with inflammatory mediators. Journal of Neuroimmunology, 137: 94-99, 2003. [Link]

Pollak Y, Ovadia H, Orion E, Yirmiya R. The EAE-associated behavioral syndrome: II. Modulation by anti-inflammatory treatments. Journal of Neuroimmunology, 137: 100-108, 2003. [Link]

Wolf G, Yirmiya R, Goshen I, Iverfeldt K, Holmlund  L, Takeda K, Shavit, Y. Impairment of interleukin-1 (IL-1) signaling reduces basal pain sensitivity in mice:  Genetic, pharmacological and developmental aspects. Pain, 104: 471-480, 2003. [Link]

2002

Barak O, Goshen I, Ben-Hur T, Weidenfeld J, Taylor AN, Yirmiya R. Involvement of brain cytokines in the neurobehavioral disturbances induced by HIV-1 gp120. Brain Research, 933: 98-108, 2002.  [Link]

Barak O, Weidenfeld J, Ben-Hur T, Taylor AN, Yirmiya R. Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary–adrenal activation in rats: Role of prostaglandins. Brain, Behavior and Immunity, 16: 720-735, 2002. [Link]

Castanon N, Leonard BE, Neveu PJ, Yirmiya R. Effects of antidepressants on cytokine production and actions. Brain, Behavior and Immunity, 16: 569-574, 2002. [Link]

Cohen O, Erb C, Ginzberg D, Pollak Y, Seidman S, Yirmiya R, Soreq H. Neuronal overexpression of “readthrough” acetylcholinesterase is associated with antisense-suppressible behavioral impairments. Molecular Psychiatry, 7: 874-885, 2002.[Link]

Dantzer R, Wollman EE, Yirmiya R. Cytokines and depression: An update. Brain, Behavior and Immunity, 16: 501-502, 2002. [Link]

Pollak Y, Orion E, Ovadia H, Yirmiya R. Experimental autoimmune encephalomyelitis-associated behavioral syndrome as a model for 'depression due to multiple sclerosis'. Brain, Behavior and Immunity, 16: 533-543, 2002.  [Link]

Pollak Y, Yirmiya R. Cytokine-induced changes in mood and behavior: Implications for “depression due to a general medical condition“, immunotherapy and antidepressive treatment. International Journal of Neuropsychopharmacology, 5: 389-399, 2002. [Link]

Pollmächer T, Haak M, Schuld A, Reichenberg A, Yirmiya R. Low levels of inflammatory cytokines – do they influence human brain functions? Brain, Behavior and Immunity, 16: 525-532, 2002. [Link]

Reichenberg A, Schuld A, Kraus T, Haak M, Pollmächer T, Yirmiya R. Endotoxin-induced anorexia in healthy human volunteers is mediated by cytokine secretion. Psychoneuroendocrinology, 27: 945-956, 2002. [Link]

Taylor A, Tio DL, Ngy SH, Yirmiya R. Alcohol consumption attenuates febrile responses to lipopolysaccharide and interleukin-1β in male rats. Alcoholism: Clinical and Experimental Research, 26: 44-52, 2002. [Link]

Taylor AN, Tritt SH, Tio D, Romeo HE, Yirmiya R. Maternal adrenalectomy abrogates the effect of fetal alcohol exposure on IL-1β -induced febrile response of adult male offspring. Neuroendocrinology, 76: 185-192, 2002. [Link]

Yirmiya R, Winocur G, Goshen I. Brain interleukin-1 is involved in spatial memory and passive avoidance conditioning. Neurobiology of Learning and Memory, 78: 379-389, 2002. [Link]

2001

Ben-Hur T, Cialic R, Itzik A, Batak O, Yirmiya R, Weidenfeld J. A novel permissive role for glucocorticoids in induction of febrile and behavioral signs of experimental herpes simplex virus encephalitis. Neurosceince, 108: 119-127, 2001. [Link]

Ben-Hur T, Cialic R, Itzik A, Yirmiya R, Weidenfeld J. Acute Effects of Purified and UV-inactivated HSV-1 on the Hypothalamic-Pituitary-Adrenocortical Axis. Neuroendocrinology, 74: 160-166, 2001. [Link]

Hodgson DM, Yirmiya R, Taylor AN. Intracerebroventricular interleukin-1β impairs clearance of tumor cells from the lungs: role of brain prostaglandins. Journal of Neuroimmunology, 119: 57-63, 2001. [Link]

Reichenberg A, Yirmiya R, Schuld A, Kraus T, Haak M, Morag A, Pollmächer T. Cytokine-mediated emotional and cognitive disturbances in humans. Archives of General Psychiatry, 58: 445-452, 2001.[Link]  

Wohlman A, Yirmiya R, Gallily R, Weidenfeld J. Effects of Mycoplasma fermentans on brain PGE2: Role of glucocorticoids and their receptors. Neuroimmunomodulation, 9: 141-147, 2001. [Link]

Yirmiya R, Pollak Y, Barak O, Avitsur R, Ovadia H, Bette M, Weihe E, Weidenfeld J. Effects of Antidepressant Drugs on the Behavioral and Physiological Responses to Lipopolysaccharide (LPS) in Rodents. Neuropsychopharmacology, 24: 531-544, 2001.[Link]

2000

Haack M, Reichenberg A, Kraus T, Schuld A, Yirmiya R, Pollmächer T. Effects of an intravenous cannula on the plasma levels of cytokines and soluble cytokine receptors. Cytokine, 12: 694-698, 2000. [Link]

Pollak Y, Ovadia H, Goshen I, Yirmiya R. Behavioral aspects of experimental allergic encephalomyelitis (EAE). Journal of Neuroimmunology, 104: 31-36, 2000. [Link]

Shohami E, Kaufer D, Seidmann S, Melamed-Book N, Cohen O, Yirmiya R, Soreq H. Antisense prevention of neuronal damage following head injury. Journal of Molecular Medicine, 78: 228-235, 2000. [Link]

Taylor A, Chiappelli F, Yirmiya R. Fetal alcohol exposure and immunity. In: Ader R, Cohen N, Felten D. (Eds.). Psychoneuroimmunology, 3rd Edition. Vol. 2, pp. 777-779. Academic Press: New York, 2000.

Yirmiya R. Depression in medical illness: The role of the immune system. Western Journal of Medicine, 173: 333-336, 2000. [Link]

Yirmiya R, Pollak Y, Morag M, Reichenberg A, Barak O, Avitsur R, Shavit Y, Ovadia H, Weidenfeld J, Morag A, Newman M, Pollmächer T. Illness, Cytokines and Depression. Annals of the New York Academy of Sciences, 917: 478-487, 2000. [Link]

1999

Avitsur R, Yirmiya R. The partner preference paradigm: a method to study sexual motivation and performance of female rats. Brain Research Protocols, 3: 320-325, 1999.  [Link]

Avitsur R, Yirmiya R. The immunobiology of sexual behavior: Gender differences in the suppression of sexual activity during illness Pharmacology, Biochemistry and Behavior, 64:787-796, 1999. [Link]

Avitsur R, Yirmiya R. Cytokines inhibit sexual behavior in female rats. I. Synergistic effects of tumor necrosis factor-α and interleukin-1. Brain, Behavior and Immunity, 13: 14-32, 1999.  [Link]

Avitsur R, Weidenfeld J, Yirmiya R. Cytokines inhibit sexual behavior in female rats. II. Prostaglandins mediate the suppressive effects of interleukin-1β. Brain, Behavior and Immunity, 13: 33-45, 1999. [Link]

Ben-Eliyahu S, Page GG, Yirmiya R, Shakhar G. Evidence that stress and surgical interventions promote tumor development by suppressing natural killer cell activity. International Journal of Cancer, 80: 880-888, 1999. [Link]

Dantzer R, Wollman EE, Vitkovik L, Yirmiya R. Cytokines and depression: Fortuitous or causative association. Molecular Psychiatry, 4:328-332, 1999. [Link]

Dantzer R, Wollman EE, Vitkovik L, Yirmiya R. Cytokines, stress and depression: Conclusions and perspectives. In : Dantzer R, Wollman EE, Yirmiya R. (eds.), Cytokines, Stress and Depression (Advances in Experimental Medicine and Biology, vol. 461), Kluwer Academic/Plenum Press, New York, 1999, pp. 317-329.[Link]

Dantzer R, Wollman EE, Yirmiya R (Eds.). Cytokines, Stress and Depression. Kluwer Academic/Plenum Press: New York, 1999.

Hodgson DM, Yirmiya R, Taylor AN. Intracerebral interleukin-1β impairs response to tumor invasion: Involvement of adrenal chatecholamines. Brain Research, 816: 200-208, 1999. [Link]

Morag M, Morag A, Reichenberg A, Lerer B, Yirmiya R. Psychological variables as predictors of rubella antibody titers and fatigue - A prospective, double blind study. Journal of Psychiatric Research, 33: 389-395, 1999. [Link]

Taylor AN, Tio DL, Yirmiya R. Fetal alcohol exposure attenuates interleukin-1β -induced fever: Neuroimmune mechanisms. Journal of Neuroimmunology, 99: 44-52, 1999. [Link]

Yirmiya R, Weidenfeld J, Pollak Y, Morag M, Morag A, Avitsur R, Barak O, Reichenberg A, Cohen E, Shavit Y, Ovadia H. Cytokines, ‘depression due to a general medical condition’ and antidepressants drugs. In: Dantzer R, Wollman EE, Yirmiya R. (Eds.). Cytokines, Stress and Depression (Advances in Experimental Medicine and Biology, vol. 461), Kluwer Academic/Plenum Press, New York, 1999, pp. 283-316. [Link]

Yirmiya R, Weidenfeld J, Barak O, Avitsur R, Pollak Y, Gallily R, Wohlman, A, Ovadia H, Ben-Hur T. The role of brain cytokines in mediating the behavioral and neuroendocrine effects of intracerebral mycoplasma fermentans. Brain Research, 829: 28-38, 1999. [Link]

1998

Hodgson DM, Yirmiya R, Taylor, AN. Intracerebral HIV glycoprotein (gp120) enhances tumor metastasis via centrally released interleukin-1. Brain Research, 781: 244-251, 1998. [Link]

Morag M, Yirmiya R, Lerer B, Morag A. Influence of socioeconomic status on behavioral, emotional and cognitive effects of rubella vaccination: A prospective, double blind study. Psychoneuroendocrinology, 23: 337-351, 1998. [Link]

Shavit Y, Cohen E, Gagin R, Avitsur R, Pollak Y, Chailin G, Wolf G, Yirmiya R. Effects of prenatal morphine exposure on NK cytotoxicity and responsiveness to LPS in rats. Pharmacology, Biochemistry, and Behavior, 59: 835-841, 1998.  [Link]

Yirmiya R, Chiappelli F, Tio D, Tritt S, Taylor AN. Effects of prenatal alcohol and pair-feeding on lipopolysaccharide induced-secretion of TNF-α and corticosterone. Alcohol, 15: 327-335, 1998. [Link]

1997

Avitsur R, Cohen E, Yirmiya R. Effects of interleukin-1 on sexual attractivity in a model of sickness behavior. Physiology and Behavior, 63: 25-30, 1997. [Link]

Avitsur R, Pollak Y, Yirmiya R. Different receptor mechanisms mediate the effects of endotoxin and interleukin-1 on female sexual behavior. Brain Research, 773: 149-161, 1997. [Link]

Avitsur R, Pollak Y, Yirmiya R. Administration of interleukin-1 into the hypothalamic paraventricular nucleus induces febrile and behavioral effects, NeuroImmunoModulation, 4: 258-265, 1997. [Link]

Chiappelli F, Kung MA, Tio DL, Tritt S, Yirmiya R, Taylor AN. Fetal alcohol exposure augments the blunting of tumor necrosis factor production in vitro resulting from in vivo priming with lipopolysaccharide in young adult male but not female rats. Alcoholism: Clinical and Experimental Research, 21: 1542-1546, 1997.  [Link]

Weidenfeld J, Yirmiya R. Effect of bacterial endotoxin on the glucocorticoid feedback regulation of adrenocortical response to stress. NeuroImmunoModulation, 3: 352-357, 1996 (published in 1997).

[Link]

Wohlman A, Gallily R, Yirmiya R, Weidenfeld J. Characterization of the effect of mycoplasma fermentans on the hypothalamo-pituitary-adrenal axis. Neuroendocrinology, 66: 221-228, 1997.  [Link]

Yirmiya R. Behavioral and psychological effects of immune activation: implications for ‘depression due to a general medical condition’. Current Opinion in Psychiatry, 10: 470-476, 1997. [Link]

Yirmiya R, Barak O, Avitsur R, Gallily R, Weidenfeld J. Intracerebral administration of Mycoplasma fermentans in rats produces sickness behavior: Involvement of prostaglandins. Brain Research, 749: 71-81, 1997. [Link]

1996

Ben-Eliyahu S, Page GG, Yirmiya R, Taylor AN. Acute alcohol intoxication suppresses natural killer cell activity in vivo and promotes tumor metastasis. Nature Medicine, 2: 457-460, 1996. [Link]

Yirmiya R. Endotoxin produces a depressive-like episode in rats. Brain Research, 711: 163-174, 1996. [Link]

Yirmiya R, Tio D, Taylor AN. Effects of Fetal alcohol exposure on fever, sickness behavior, and pituitary adrenal activation induced by interleukin-1β  in young adult rats. Brain, Behavior and Immunity, 10: 205-220, 1996. [Link]

1995

Avitsur R, Donchin O, Barak O, Cohen E, Yirmiya R. Behavioral effects of interleukin-1β: Modulation by gender, estrus cycle and progesterone. Brain, Behavior and Immunity, 9: 234-241, 1995. [Link]

Yirmiya R, Avitsur R, Donchin O, Cohen E. Interleukin-1 inhibits sexual behavior in female but not in male rats. Brain, Behavior and Immunity, 9: 220-233, 1995. [Link]

1994

Yirmiya R, Rosen H, Donchin O, Ovadia H. Behavioral effects of lipopolysaccharide in rats: Involvement of endogenous opioids. Brain Research, 648: 80-86, 1994.[Link]

1993

Ben-Eliyahu S, Yirmiya R, Page GG, Chiappelli F, Liebeskind JC, Taylor AN. Ethanol, natural killer cells, and tumor progression in rats. Advances in the Biosciences, 86: 377-386, 1993.

Chiappelli F, Wong C, Yirmiya R, Norman D, Chang MP, Taylor AN. Fetal alcohol exposure and neuroimmune surveillance, In: Alcohol, Immunity and Cancer, edited by R. Yirmiya and A. N. Taylor, CRC Press Inc.,  1993, pp. 257-286.

Mogil JS, Marek P, Yirmiya R, Balian H, Sadowski B, Taylor AN, Liebeskind JC. Antagonism of the non-opioid component of ethanol-induced analgesia by the NMDA receptor antagonist MK-801. Brain Research, 602: 126-130, 1993. [Link]

Page GG, Ben-Eliyahu S, Yirmiya R, Liebeskind JC. Morphine attenuates surgery-induced enhancement of metastatic colonization in rats. Pain, 54: 21-28, 1993. [Link]

Taylor AN, Ben-Eliyahu S, Yirmiya R, Chang MP, Norman DC, Chiappelli F, Actions of alcohol on immunity and neoplasia in fetal alcohol exposed and adult rats. Alcohol and Alcoholism, 2 (Supp.): 69-74, 1993.[Link]

Yirmiya R, Ben-Eliyahu S, Taylor AN, Alcohol and Cancer:  Biochemical and Immunobiological Mechanisms. In: Alcohol, Immunity and Cancer, edited by R. Yirmiya and A. N. Taylor, CRC Press Inc., 1993, pp. 143-156.

Yirmiya R, Ben-Eliyahu S, Page GG, Donchin O, Cohen E, Shavit Y, Liebeskind JC, Taylor AN, Ethanol-induced facilitation of tumor metastases: Effects of immune modulation and interaction with stress. Advances in the Biosciences, 86: 421-425, 1993. [Link]

Yirmiya R, Pilati ML, Chiappelli F, Taylor AN. Fetal alcohol exposure attenuates lipopolysaccharide (LPS)-induced fever in rats. Alcoholism: Clinical and Experimental Research, 17: 906-910, 1993. [Link]

Yirmiya R, Taylor AN (Eds.). Alcohol, Immunity and Cancer. CRC Press: Boca Raton, 1993.

1992

Yirmiya R, Ben-Eliyahu S, Gale RP, Shavit Y, Liebeskind JC, Taylor AN. Ethanol increases tumor progression in rats: Possible involvement of natural killer cells. Brain, Behavior and Immunity, 6: 74-86, 1992. [Link]

1991

Ben-Eliyahu S, Yirmiya R, Taylor AN, Gale RP, Liebeskind JC. Stress increases metastatic spread of a mammary tumor in rats:  Evidence for mediation by the immune system. Brain, Behavior and Immunity, 5: 193-205, 1991. [Link]

Lieblich I, Yirmiya R, Liebeskind JC. Intake of and preference for sweet solutions is attenuated in morphine-withdrawn rats. Behavioral Neuroscience, 105: 965-970, 1991. [Link]

Marek P, Yirmiya R, Liebeskind JC. Stimulation-produced analgesia in the mouse: Evidence for laterality of opioid mediation. Brain Research, 541: 154-156, 1991. [Link]

Yirmiya R. Interaktionen zwischen immunfunktionen und zentralem nervensystem (Interactions of immune and central nervous system processes). Onkologie, 14 (Suppl.): 16-18, 1991.

Yirmiya R, Shavit Y, Ben-Eliyahu S, Gale RP, Liebeskind JC, Taylor AN, Weiner H. Modulation of immunity and neoplasia by neuropeptides released by stressors. In: Stress, Neuropeptides, and  Systemic Disease, edited by P. G. Kaufmann JA, McCubbin, Nemeroff CB. Academic Press, 1991, pp. 261-286. [Link]

1990

Ben-Eliyahu S, Yirmiya R, Shavit Y, Liebeskind JC. Stress-induced suppression of natural killer cell cytotoxicity in the rat: A naltrexone-insensitive paradigm. Behavioral Neuroscience, 104: 235-238, 1990. [Link]

Hocherman S, Yirmiya R. Neuronal activity in the medial geniculate nucleus and the auditory cortex reflects signal anticipation. Brain, 113: 1707-1720, 1990. [Link]

Marek P, Yirmiya R, Liebeskind JC. Genetic influences on brain stimulation-produced analgesia in mice: II. Correlation with brain opiate receptor concentration. Brain Research, 507: 155-157, 1990. [Link]

Shavit, Y., Yirmiya, R., and Beilin, B., Stress neuropeptides, immunity and neoplasia. In: The Neuroendocrine Immune Network, edited by Z. Freier, CRC Press, Boca Raton, Florida, 1990, pp. 163-175. [Link]

Yirmiya R, Ben-Eliyahu S, Shavit Y, Marek P, Liebeskind JC. Stimulation of the hypothalamic paraventricular nucleus (PVN) produces analgesia not mediated by vasopressin or endogenous opioids. Brain Research, 537: 169-174, 1990. [Link]

1989

Holder MD, Yirmiya R. Behavioral assessment of the toxicity of aspartame. Pharmacology Biochemistry and Behavior, 32: 17-26, 1989. [Link]

Holder MD, Yirmiya R, Garcia J, Raizer J. Conditioned taste aversions not readily disrupted by external excitation. Behavioral Neuroscience, 103: 605-611, 1989. [Link]

Marek P, Yirmiya R, Panocka I, Liebeskind JC. Genetic influence on brain stimulation-produced analgesia in mice: I. Correlation with stress-induced analgesia. Brain Research, 489: 182-184, 1989. [Link]

Morgan MM, Yirmiya R, Marek P, Liebeskind JC. Natural mechanisms of pain inhibition. In: Drug Treatment of Cancer Pain in a Drug-oriented Society. Advances in Pain Research and Therapy, Vol. 11, edited by C. S. Hill and W. S. Fields, Raven Press, New York, 1989, pp. 311-318. [Link]

Yirmiya R, Levin E, Chapman CD, Garcia J. Morphological and behavioral effects of perinatal exposure to aspartame (NutrasweetR) on rat pups. Bulletin of the Psychonomic Society, 27: 153-156, 1989. [Link]

Yirmiya R, Shavit Y, Ben-Eliyahu S, Martin FC, Weiner H, Liebeskind JC. Natural Killer cell activity in-deficient rats (Brattleboro strain). Brain Research, 479: 16-22, 1989. [Link]

Yirmiya R, Taylor AN. Genetic differences in opiate receptor concentration and sensitivity to ethanol's effects. Pharmacology, Biochemistry and Behavior, 33: 793-796, 1989. [Link]

1988

Marek P, Yirmiya R, Liebeskind JC. Strain differences in the magnitude of swimming-induced analgesia correlate with brain opiate receptor concentration. Brain Research, 447: 188-190, 1988. [Link]

Yirmiya R, Holder MD, Derdearian A. Salt preference in rats with hereditary hypothalamic diabetes insipidus (Brattleboro strain). Behavioral Neuroscience, 102: 574-579, 1988. [Link]

Yirmiya R, Lieblich I, Liebeskind JC. Reduced saccharin preference in CXBK (opioid receptor-deficient) mice. Brain Research, 438: 339-342, 1988. [Link]

Yirmiya R, Lieblich I, Liebeskind JC, Garcia J. Lithium chloride produces illness-induced analgesia. Bulletin of the Psychonomic Society, 26: 261-262, 1988. [Link]

Yirmiya R, Zhou FC, Holder MD, Deems DA, Garcia J. Partial recovery of gustatory function after neural tissue transplantation to the lesioned gustatory neocortex. Brain Research Bulletin, 20: 619-625, 1988. [Link]

1987

Holder MD, Leon M, Yirmiya R, Garcia J. Effect of taste preexposure on taste and odor aversions. Animal Learning and Behavior, 15: 55-63, 1987. [Link]

Lieblich I, Yirmiya R. Naltrexone reverses a long-term depressive effect of a toxic LiCl injection on saccharin preference. Physiology and Behavior, 39: 547-550, 1987. [Link]

Shavit Y, Martin FC, Yirmiya R, Ben-Eliyahu S, Terman GW, Weiner H, Gale RP, Liebeskind JC. Effects of a single administration of morphine or footshock stress on natural killer cell cytotoxicity. Brain, Behavior and Immunity, 1: 318-328, 1987. [Link]

Yirmiya R, Hocherman S. Auditory- and movement-related neural activity interact in the pulvinar of the behaving rhesus monkey. Brain Research, 402: 93-102, 1987. [Link]

Yirmiya R, Holder MD. Effects of naloxone and cholecystokinin on food and water intake in vasopressin-deficient rats (Brattleboro strain). Peptides, 8: 763-768, 1987.  [Link]

Yirmiya R, Holder MD, Garcia, J., Conditioned taste aversion in vasopressin-deficient rats (Brattleboro strain). Physiology and Behavior, 39: 489-493, 1987. [Link]

Yirmiya, R., Lieblich, I., Garcia, J., and Liebeskind, J. C., Analgesic properties of lithium. Proceedings of the Western Pharmacology Society, 30: 303-306, 1987. [Link]