Urea + choline chloride (Reline)

 

Urea + choline chloride osmotic pressure at 2:1 mole ratio and other ratios 

 

1) Urea + choline chloride osmotic pressure at 2:1 (Reline) mole ratio and 25 degrees Celsius

We define Reline as two urea and one choline chloride molecules. When mixed together at this 2:1 (urea:cholinechloride mole ratio) ratio, they form a deep eutectic solvent, termed Reline. A 1mol/kg Reline solution contains 2 mol/kg urea and 1mol/kg choline chloride. 

References

Please use the following reference when using this data. 

Shumilin, Ilan, Ahmad Tanbuz, and Daniel Harries. "Deep Eutectic Solvents for Efficient Drug Solvation: Optimizing Composition and Ratio for Solubility of β-Cyclodextrin." Pharmaceutics 15, no. 5 (2023): 1462. https://10.3390/pharmaceutics15051462

Shumilin et al
molality, mol/kgOsmolality, Osmolal
0.2030.544
0.4221.287
0.4281.374
0.4281.334
0.9533.059
0.9602.952
0.9622.927
1.6475.040
1.6495.247
1.6505.182
2.5558.171
2.5597.980
2.5688.086
3.82112.324
3.84712.603
3.87312.682
5.75719.158
5.78119.388
5.78319.485
8.78729.954
9.01130.589
9.01230.488
11.57238.143
15.30449.673
15.33249.499
15.36847.205
16.37750.126
17.49953.130
18.75156.666
20.16059.050
21.75762.801
23.57966.106
25.68370.069
28.13574.475
31.03277.851
34.50681.680
34.62486.986
34.65187.101
38.74788.430
44.04794.288
50.848102.674
59.902110.068
72.544117.885

The data set is adequately captured by the following cubic term:
Osmolal = 0.00023*m^3 - 0.04598*m^2 + 3.75984*m

2) Urea + choline chloride osmotic pressure at all ratios

References

Please use the following reference when using this data:

Shumilin, Ilan, Ahmad Tanbuz, and Daniel Harries. "Deep Eutectic Solvents for Efficient Drug Solvation: Optimizing Composition and Ratio for Solubility of β-Cyclodextrin." Pharmaceutics 15, no. 5 (2023): 1462. https://10.3390/pharmaceutics15051462

Shumilin et al.
[urea], mol/kg[choline chloride], mol/kgOsmolality, Osmolal
0.25715.92841.008
0.4060.2030.558
0.8440.4221.293
0.8550.4281.350
0.9984.99910.687
1.0002.0004.271
1.00910.45025.581
1.70015.75741.241
1.9060.9533.084
1.9200.9602.967
1.9250.9622.908
1.9999.92524.881
2.30115.68441.241
2.78815.62641.241
2.9984.99912.120
3.02210.45027.007
3.2951.6475.057
3.2971.6495.239
3.3001.6505.178
3.97215.48641.124
4.0022.0006.537
4.87510.45028.010
4.9874.99913.448
5.00519.78754.343
5.0129.92526.558
5.1092.5558.186
5.1182.5597.993
5.1362.5688.057
5.46618.13847.668
5.65218.70548.194
6.84424.23567.259
6.9804.99914.737
6.98415.12541.241
7.0222.0008.768
7.34625.85467.633
7.6433.82112.327
7.6943.84712.606
7.7473.87312.675
7.8379.92528.010
7.96310.45029.502
9.0251.99910.151
9.92410.45030.647
9.9354.99916.728
10.14219.97853.318
10.98714.64841.828
11.0002.00011.570
11.0189.92529.691
11.5145.75719.184
11.5615.78119.420
11.5665.78319.499
11.82321.67057.223
11.95319.78755.840
12.62310.45031.915
12.9891.99913.096
13.0035.00018.637
13.50828.06171.721
13.9879.92531.131
14.7922.00014.304
14.9015.00019.815
14.94910.45033.112
15.42614.11842.183
15.46828.33275.052
16.9341.23315.028
16.9709.92532.511
17.3984.99921.426
17.5738.78729.976
17.8842.48617.332
18.0219.01130.551
18.0241.99916.653
18.0259.01230.455
18.06410.45034.439
18.3482.00016.878
18.40019.78657.379
18.5341.66216.578
18.6995.00022.249
18.8513.76219.974
19.1991.79117.105
19.2574.30021.263
19.29913.65542.540
19.7241.89817.408
19.9359.92533.925
20.15010.45035.376
20.21723.94162.612
20.6306.11325.581
20.67925.92766.518
20.7653.09420.214
21.00013.45342.779
21.4413.04520.534
21.6077.40128.844
21.8449.92534.853
21.9081.92018.949
21.97613.33642.659
22.2978.31231.326
22.9203.52822.083
23.14511.57238.176
23.3349.68234.957
23.89410.42036.758
24.9805.79827.643
25.15312.95642.899
25.3393.85923.677
25.52632.36979.284
25.74019.78759.123
25.75512.87843.020
25.76212.88343.140
26.7909.92536.974
27.5786.48129.881
28.8806.56730.551
30.06627.81471.119
30.59535.51785.654
30.60815.30449.669
30.66515.33249.533
30.73615.36847.146
31.0339.68238.286
31.1377.13631.326
31.34131.05076.135
32.75416.37750.078
32.96419.78660.757
34.99617.49953.173
35.1159.74638.731
36.31613.07147.276
36.31819.78761.257
36.67311.57343.748
37.50118.75156.604
39.84337.49886.439
40.32020.16059.123
40.38412.36245.107
40.39531.87676.135
43.00117.36057.379
43.51321.75762.783
44.31419.78763.129
46.04615.32052.884
47.16023.57966.152
48.56116.98254.343
50.57440.29389.136
51.36625.68370.128
51.92923.08769.155
54.45546.84997.792
56.27128.13574.412
56.40025.95674.624
57.02738.41886.968
57.41943.79694.046
58.61623.85770.325
62.06531.03277.912
62.94830.15781.408
66.89732.68985.138
69.01334.50681.649
69.25034.62486.968
69.26827.16069.737
69.30234.65186.968
72.09436.02489.972
72.73849.28493.744
73.99631.35777.687
74.84032.94085.138
77.49638.74788.313
79.32458.664105.767
81.11136.45090.253
86.63539.54294.653
87.73550.49698.770
88.09444.04794.348
95.25661.765107.663
101.69650.848102.509
103.31444.52095.267
106.43744.92989.136
109.14452.144108.051
109.83251.60898.442
111.96160.024106.518
119.80559.902110.028
125.93661.544115.525
132.93670.856114.207
143.84665.185112.078
145.09272.544117.792
149.91274.967126.279
150.70175.259116.874
160.67280.339115.525
163.93081.959122.124
169.496101.496128.480
212.445118.085135.658
241.004114.722140.318
365.581195.946147.737
394.787193.131162.154
416.403216.096154.479
827.672413.745167.552
831.636415.870166.430
847.309423.549162.154
862.053431.040159.150