Urea + choline chloride osmotic pressure at 2:1 mole ratio and other ratios
1) Urea + choline chloride osmotic pressure at 2:1 (Reline) mole ratio and 25 degrees Celsius
We define Reline as two urea and one choline chloride molecules. When mixed together at this 2:1 (urea:cholinechloride mole ratio) ratio, they form a deep eutectic solvent, termed Reline. A 1mol/kg Reline solution contains 2 mol/kg urea and 1mol/kg choline chloride.
References
Please use the following reference when using this data.
Shumilin, Ilan, Ahmad Tanbuz, and Daniel Harries. "Deep Eutectic Solvents for Efficient Drug Solvation: Optimizing Composition and Ratio for Solubility of β-Cyclodextrin." Pharmaceutics 15, no. 5 (2023): 1462. https://10.3390/pharmaceutics15051462.
Shumilin et al | |
molality, mol/kg | Osmolality, Osmolal |
0.203 | 0.544 |
0.422 | 1.287 |
0.428 | 1.374 |
0.428 | 1.334 |
0.953 | 3.059 |
0.960 | 2.952 |
0.962 | 2.927 |
1.647 | 5.040 |
1.649 | 5.247 |
1.650 | 5.182 |
2.555 | 8.171 |
2.559 | 7.980 |
2.568 | 8.086 |
3.821 | 12.324 |
3.847 | 12.603 |
3.873 | 12.682 |
5.757 | 19.158 |
5.781 | 19.388 |
5.783 | 19.485 |
8.787 | 29.954 |
9.011 | 30.589 |
9.012 | 30.488 |
11.572 | 38.143 |
15.304 | 49.673 |
15.332 | 49.499 |
15.368 | 47.205 |
16.377 | 50.126 |
17.499 | 53.130 |
18.751 | 56.666 |
20.160 | 59.050 |
21.757 | 62.801 |
23.579 | 66.106 |
25.683 | 70.069 |
28.135 | 74.475 |
31.032 | 77.851 |
34.506 | 81.680 |
34.624 | 86.986 |
34.651 | 87.101 |
38.747 | 88.430 |
44.047 | 94.288 |
50.848 | 102.674 |
59.902 | 110.068 |
72.544 | 117.885 |
The data set is adequately captured by the following cubic term:
Osmolal = 0.00023*m^3 - 0.04598*m^2 + 3.75984*m
2) Urea + choline chloride osmotic pressure at all ratios
References
Please use the following reference when using this data:
Shumilin, Ilan, Ahmad Tanbuz, and Daniel Harries. "Deep Eutectic Solvents for Efficient Drug Solvation: Optimizing Composition and Ratio for Solubility of β-Cyclodextrin." Pharmaceutics 15, no. 5 (2023): 1462. https://10.3390/pharmaceutics15051462.
Shumilin et al. | ||
[urea], mol/kg | [choline chloride], mol/kg | Osmolality, Osmolal |
0.257 | 15.928 | 41.008 |
0.406 | 0.203 | 0.558 |
0.844 | 0.422 | 1.293 |
0.855 | 0.428 | 1.350 |
0.998 | 4.999 | 10.687 |
1.000 | 2.000 | 4.271 |
1.009 | 10.450 | 25.581 |
1.700 | 15.757 | 41.241 |
1.906 | 0.953 | 3.084 |
1.920 | 0.960 | 2.967 |
1.925 | 0.962 | 2.908 |
1.999 | 9.925 | 24.881 |
2.301 | 15.684 | 41.241 |
2.788 | 15.626 | 41.241 |
2.998 | 4.999 | 12.120 |
3.022 | 10.450 | 27.007 |
3.295 | 1.647 | 5.057 |
3.297 | 1.649 | 5.239 |
3.300 | 1.650 | 5.178 |
3.972 | 15.486 | 41.124 |
4.002 | 2.000 | 6.537 |
4.875 | 10.450 | 28.010 |
4.987 | 4.999 | 13.448 |
5.005 | 19.787 | 54.343 |
5.012 | 9.925 | 26.558 |
5.109 | 2.555 | 8.186 |
5.118 | 2.559 | 7.993 |
5.136 | 2.568 | 8.057 |
5.466 | 18.138 | 47.668 |
5.652 | 18.705 | 48.194 |
6.844 | 24.235 | 67.259 |
6.980 | 4.999 | 14.737 |
6.984 | 15.125 | 41.241 |
7.022 | 2.000 | 8.768 |
7.346 | 25.854 | 67.633 |
7.643 | 3.821 | 12.327 |
7.694 | 3.847 | 12.606 |
7.747 | 3.873 | 12.675 |
7.837 | 9.925 | 28.010 |
7.963 | 10.450 | 29.502 |
9.025 | 1.999 | 10.151 |
9.924 | 10.450 | 30.647 |
9.935 | 4.999 | 16.728 |
10.142 | 19.978 | 53.318 |
10.987 | 14.648 | 41.828 |
11.000 | 2.000 | 11.570 |
11.018 | 9.925 | 29.691 |
11.514 | 5.757 | 19.184 |
11.561 | 5.781 | 19.420 |
11.566 | 5.783 | 19.499 |
11.823 | 21.670 | 57.223 |
11.953 | 19.787 | 55.840 |
12.623 | 10.450 | 31.915 |
12.989 | 1.999 | 13.096 |
13.003 | 5.000 | 18.637 |
13.508 | 28.061 | 71.721 |
13.987 | 9.925 | 31.131 |
14.792 | 2.000 | 14.304 |
14.901 | 5.000 | 19.815 |
14.949 | 10.450 | 33.112 |
15.426 | 14.118 | 42.183 |
15.468 | 28.332 | 75.052 |
16.934 | 1.233 | 15.028 |
16.970 | 9.925 | 32.511 |
17.398 | 4.999 | 21.426 |
17.573 | 8.787 | 29.976 |
17.884 | 2.486 | 17.332 |
18.021 | 9.011 | 30.551 |
18.024 | 1.999 | 16.653 |
18.025 | 9.012 | 30.455 |
18.064 | 10.450 | 34.439 |
18.348 | 2.000 | 16.878 |
18.400 | 19.786 | 57.379 |
18.534 | 1.662 | 16.578 |
18.699 | 5.000 | 22.249 |
18.851 | 3.762 | 19.974 |
19.199 | 1.791 | 17.105 |
19.257 | 4.300 | 21.263 |
19.299 | 13.655 | 42.540 |
19.724 | 1.898 | 17.408 |
19.935 | 9.925 | 33.925 |
20.150 | 10.450 | 35.376 |
20.217 | 23.941 | 62.612 |
20.630 | 6.113 | 25.581 |
20.679 | 25.927 | 66.518 |
20.765 | 3.094 | 20.214 |
21.000 | 13.453 | 42.779 |
21.441 | 3.045 | 20.534 |
21.607 | 7.401 | 28.844 |
21.844 | 9.925 | 34.853 |
21.908 | 1.920 | 18.949 |
21.976 | 13.336 | 42.659 |
22.297 | 8.312 | 31.326 |
22.920 | 3.528 | 22.083 |
23.145 | 11.572 | 38.176 |
23.334 | 9.682 | 34.957 |
23.894 | 10.420 | 36.758 |
24.980 | 5.798 | 27.643 |
25.153 | 12.956 | 42.899 |
25.339 | 3.859 | 23.677 |
25.526 | 32.369 | 79.284 |
25.740 | 19.787 | 59.123 |
25.755 | 12.878 | 43.020 |
25.762 | 12.883 | 43.140 |
26.790 | 9.925 | 36.974 |
27.578 | 6.481 | 29.881 |
28.880 | 6.567 | 30.551 |
30.066 | 27.814 | 71.119 |
30.595 | 35.517 | 85.654 |
30.608 | 15.304 | 49.669 |
30.665 | 15.332 | 49.533 |
30.736 | 15.368 | 47.146 |
31.033 | 9.682 | 38.286 |
31.137 | 7.136 | 31.326 |
31.341 | 31.050 | 76.135 |
32.754 | 16.377 | 50.078 |
32.964 | 19.786 | 60.757 |
34.996 | 17.499 | 53.173 |
35.115 | 9.746 | 38.731 |
36.316 | 13.071 | 47.276 |
36.318 | 19.787 | 61.257 |
36.673 | 11.573 | 43.748 |
37.501 | 18.751 | 56.604 |
39.843 | 37.498 | 86.439 |
40.320 | 20.160 | 59.123 |
40.384 | 12.362 | 45.107 |
40.395 | 31.876 | 76.135 |
43.001 | 17.360 | 57.379 |
43.513 | 21.757 | 62.783 |
44.314 | 19.787 | 63.129 |
46.046 | 15.320 | 52.884 |
47.160 | 23.579 | 66.152 |
48.561 | 16.982 | 54.343 |
50.574 | 40.293 | 89.136 |
51.366 | 25.683 | 70.128 |
51.929 | 23.087 | 69.155 |
54.455 | 46.849 | 97.792 |
56.271 | 28.135 | 74.412 |
56.400 | 25.956 | 74.624 |
57.027 | 38.418 | 86.968 |
57.419 | 43.796 | 94.046 |
58.616 | 23.857 | 70.325 |
62.065 | 31.032 | 77.912 |
62.948 | 30.157 | 81.408 |
66.897 | 32.689 | 85.138 |
69.013 | 34.506 | 81.649 |
69.250 | 34.624 | 86.968 |
69.268 | 27.160 | 69.737 |
69.302 | 34.651 | 86.968 |
72.094 | 36.024 | 89.972 |
72.738 | 49.284 | 93.744 |
73.996 | 31.357 | 77.687 |
74.840 | 32.940 | 85.138 |
77.496 | 38.747 | 88.313 |
79.324 | 58.664 | 105.767 |
81.111 | 36.450 | 90.253 |
86.635 | 39.542 | 94.653 |
87.735 | 50.496 | 98.770 |
88.094 | 44.047 | 94.348 |
95.256 | 61.765 | 107.663 |
101.696 | 50.848 | 102.509 |
103.314 | 44.520 | 95.267 |
106.437 | 44.929 | 89.136 |
109.144 | 52.144 | 108.051 |
109.832 | 51.608 | 98.442 |
111.961 | 60.024 | 106.518 |
119.805 | 59.902 | 110.028 |
125.936 | 61.544 | 115.525 |
132.936 | 70.856 | 114.207 |
143.846 | 65.185 | 112.078 |
145.092 | 72.544 | 117.792 |
149.912 | 74.967 | 126.279 |
150.701 | 75.259 | 116.874 |
160.672 | 80.339 | 115.525 |
163.930 | 81.959 | 122.124 |
169.496 | 101.496 | 128.480 |
212.445 | 118.085 | 135.658 |
241.004 | 114.722 | 140.318 |
365.581 | 195.946 | 147.737 |
394.787 | 193.131 | 162.154 |
416.403 | 216.096 | 154.479 |
827.672 | 413.745 | 167.552 |
831.636 | 415.870 | 166.430 |
847.309 | 423.549 | 162.154 |
862.053 | 431.040 | 159.150 |